David James (cell biologist)
Encyclopedia
David Ernest James is a cell biologist
who discovered the glucose transporter GLUT4
. He has also been responsible for the molecular dissection of the intracellular trafficking pathways that regulate GLUT4 translocation to the cell surface, the topological mapping of the insulin signal transduction pathway, the creation of a method for studying in vivo metabolism in small animals, and the use of this method to gain insights into whole-animal fuel metabolism and homeostasis.
He is currently holds joint appointments at the Garvan Institute of Medical Research
and the University of New South Wales
, Australia.
Cell biology
Cell biology is a scientific discipline that studies cells – their physiological properties, their structure, the organelles they contain, interactions with their environment, their life cycle, division and death. This is done both on a microscopic and molecular level...
who discovered the glucose transporter GLUT4
GLUT4
Glucose transporter type 4, also known as GLUT4, is a protein that in humans is encoded by the GLUT4 gene. GLUT4 is the insulin-regulated glucose transporter found in adipose tissues and striated muscle that is responsible for insulin-regulated glucose translocation into the cell...
. He has also been responsible for the molecular dissection of the intracellular trafficking pathways that regulate GLUT4 translocation to the cell surface, the topological mapping of the insulin signal transduction pathway, the creation of a method for studying in vivo metabolism in small animals, and the use of this method to gain insights into whole-animal fuel metabolism and homeostasis.
He is currently holds joint appointments at the Garvan Institute of Medical Research
Garvan Institute of Medical Research
The Garvan Institute of Medical Research was founded in 1963 by the Sisters of Charity. Initially a research department of St Vincent's Hospital in Sydney, it is now one of Australia's largest medical research institutions with approximately 500 scientists, students and support staff.Funds for its...
and the University of New South Wales
University of New South Wales
The University of New South Wales , is a research-focused university based in Kensington, a suburb in Sydney, New South Wales, Australia...
, Australia.
See also
- GLUT 4