Deoxycytidylate C-methyltransferase
Encyclopedia
In enzymology, a deoxycytidylate C-methyltransferase is an enzyme
that catalyzes
the chemical reaction
Thus, the two substrates
of this enzyme are 5,10-methylenetetrahydrofolic acid and dCMP
, whereas its two products
are dihydrofolic acid
and deoxy-5-methylcytidylic acid.
This enzyme belongs to the family of transferase
s, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is 5,10-methylenetetrahydrofolate:dCMP C-methyltransferase. Other names in common use include deoxycytidylate methyltransferase, and dCMP methyltransferase.
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
that catalyzes
Catalysis
Catalysis is the change in rate of a chemical reaction due to the participation of a substance called a catalyst. Unlike other reagents that participate in the chemical reaction, a catalyst is not consumed by the reaction itself. A catalyst may participate in multiple chemical transformations....
the chemical reaction
Chemical reaction
A chemical reaction is a process that leads to the transformation of one set of chemical substances to another. Chemical reactions can be either spontaneous, requiring no input of energy, or non-spontaneous, typically following the input of some type of energy, such as heat, light or electricity...
- 5,10-methylenetetrahydrofolate + dCMP
dihydrofolate + deoxy-5-methylcytidylate
Thus, the two substrates
Substrate (biochemistry)
In biochemistry, a substrate is a molecule upon which an enzyme acts. Enzymes catalyze chemical reactions involving the substrate. In the case of a single substrate, the substrate binds with the enzyme active site, and an enzyme-substrate complex is formed. The substrate is transformed into one or...
of this enzyme are 5,10-methylenetetrahydrofolic acid and dCMP
DCMP
DCMP may refer to:*DC Motema Pembe, a football club of the Democratic Republic of the Congo*Deoxycytidine monophosphate*Dynamic Core Based Multicast Routing Protocol, a Multicast routing protocol...
, whereas its two products
Product (chemistry)
Product are formed during chemical reactions as reagents are consumed. Products have lower energy than the reagents and are produced during the reaction according to the second law of thermodynamics. The released energy comes from changes in chemical bonds between atoms in reagent molecules and...
are dihydrofolic acid
Dihydrofolic acid
Dihydrofolic acid is a folic acid derivative acted upon by dihydrofolate reductase to produce tetrahydrofolic acid. Since tetrahydrofolate is needed to make both purines and pyrimidines, dihydrofolate reductase is targeted by various drugs to prevent nucleic acid synthesis. Dihydrofolic acid is...
and deoxy-5-methylcytidylic acid.
This enzyme belongs to the family of transferase
Transferase
In biochemistry, a transferase is an enzyme that catalyzes the transfer of a functional group from one molecule to another . For example, an enzyme that catalyzed this reaction would be a transferase:In this example, A would be the donor, and B would be the acceptor...
s, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is 5,10-methylenetetrahydrofolate:dCMP C-methyltransferase. Other names in common use include deoxycytidylate methyltransferase, and dCMP methyltransferase.