Downstream (bioprocess)
Encyclopedia
The downstream part of a bioprocess refers to the part where the cell mass from the upstream
are processed to meet purity and quality requirements. Downstream processing is usually divided into three main sections, a capture section, a purification section and a polishing section.
Upstream (bioprocess)
The upstream part of a bioprocess refers to the first step in which biomolecules are grown, usually by bacterial or mammalian cell lines , in bioreactors. When they reach the desired density they are harvested and moved to the downstream section of the bioprocess....
are processed to meet purity and quality requirements. Downstream processing is usually divided into three main sections, a capture section, a purification section and a polishing section.