Du145
Encyclopedia
DU145 and PC3
human prostate cancer
cell lines are the "classical" cell lines of prostatic cancer. DU145 cells have moderate metastatic
potential compared to PC3 cells which have high metastatic potential.
The DU145 cell line was derived from brain metastasis. DU145 are not hormone sensitive and don’t express PSA (Prostate Specific Antigen
).
Pc3
PC3 and DU145 human prostate cancer cell lines are the "classical" cell lines of prostatic cancer. PC3 cells have high metastatic potential compared to DU145 cells which have a moderate metastatic potential....
human prostate cancer
Prostate cancer
Prostate cancer is a form of cancer that develops in the prostate, a gland in the male reproductive system. Most prostate cancers are slow growing; however, there are cases of aggressive prostate cancers. The cancer cells may metastasize from the prostate to other parts of the body, particularly...
cell lines are the "classical" cell lines of prostatic cancer. DU145 cells have moderate metastatic
Metastasis
Metastasis, or metastatic disease , is the spread of a disease from one organ or part to another non-adjacent organ or part. It was previously thought that only malignant tumor cells and infections have the capacity to metastasize; however, this is being reconsidered due to new research...
potential compared to PC3 cells which have high metastatic potential.
The DU145 cell line was derived from brain metastasis. DU145 are not hormone sensitive and don’t express PSA (Prostate Specific Antigen
Prostate specific antigen
Prostate-specific antigen also known as gamma-seminoprotein or kallikrein-3 is a glycoprotein that in humans is encoded by the KLK3 gene. KLK3 is a member of the kallikrein-related peptidase family that are secreted by the epithelial cells of the prostate gland...
).