Effective dose (pharmacology)
Encyclopedia
An effective dose in pharmacology
is the dose or amount of drug
that produces a therapeutic response or desired effect in some fraction of the subjects taking it.
The "median effective dose" is the dose that prodcues a quantal effect (all or nothing) in 50% of the population that takes it (median referring to the 50% population base). It is also sometimes abbreviated as the ED50, meaning "effective dose, for 50% of people given it". The ED50 is commonly used as a measure of reasonable expectance of a drug effect, but not necessarily the dose that a clinician might use. This depends on the need for the effect, and also the toxicity.
The ED95 is the dose required for desired effect in 95% of the population exposed to it. ED95 is more important is (for example) general anesthesia.
Pharmacology
Pharmacology is the branch of medicine and biology concerned with the study of drug action. More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function...
is the dose or amount of drug
Medication
A pharmaceutical drug, also referred to as medicine, medication or medicament, can be loosely defined as any chemical substance intended for use in the medical diagnosis, cure, treatment, or prevention of disease.- Classification :...
that produces a therapeutic response or desired effect in some fraction of the subjects taking it.
The "median effective dose" is the dose that prodcues a quantal effect (all or nothing) in 50% of the population that takes it (median referring to the 50% population base). It is also sometimes abbreviated as the ED50, meaning "effective dose, for 50% of people given it". The ED50 is commonly used as a measure of reasonable expectance of a drug effect, but not necessarily the dose that a clinician might use. This depends on the need for the effect, and also the toxicity.
The ED95 is the dose required for desired effect in 95% of the population exposed to it. ED95 is more important is (for example) general anesthesia.
See also
- List of abbreviations used in medical prescriptions
- Certain safety factorCertain safety factorThe Certain Safety Factor is the ratio of the lethal dose to 1% of population to the effective dose to 99% of the population . This is a better safety index than the LD50 for materials that have both desirable and undesirable effects, because it factors in the ends of the spectrum where doses may...