Epstein-Barr virus nuclear antigen (EBNA) IRES
Encyclopedia
This family represents an Epstein-Barr virus
internal ribosome entry site
(IRES) which is found in the U leader exon in the 5' UTR of the Epstein-Barr nuclear antigen 1 (EBNA1) gene. The EBNA IRES allows EBNA1 translation to occur under situations where initiation from the 5' cap structure and ribosome
scanning is reduced. It is thought that the EBNA IRES is necessary for the regulation of latent gene expression.
Epstein-Barr virus
The Epstein–Barr virus , also called human herpesvirus 4 , is a virus of the herpes family and is one of the most common viruses in humans. It is best known as the cause of infectious mononucleosis...
internal ribosome entry site
Internal ribosome entry site
An internal ribosome entry site, abbreviated IRES, is a nucleotide sequence that allows for translation initiation in the middle of a messenger RNA sequence as part of the greater process of protein synthesis...
(IRES) which is found in the U leader exon in the 5' UTR of the Epstein-Barr nuclear antigen 1 (EBNA1) gene. The EBNA IRES allows EBNA1 translation to occur under situations where initiation from the 5' cap structure and ribosome
Ribosome
A ribosome is a component of cells that assembles the twenty specific amino acid molecules to form the particular protein molecule determined by the nucleotide sequence of an RNA molecule....
scanning is reduced. It is thought that the EBNA IRES is necessary for the regulation of latent gene expression.