State Road 349 is a 2 lane Florida State Road in eastern Dixie

Dixie County, Florida

Dixie County is a county located in the U.S. state of Florida. As of 2000, the population was 13,827. The U.S. Census Bureau 2005 estimate for the county is 14,647 . Its county seat is Cross City, Florida.- History :...

 and Lafayette

Lafayette County, Florida

Lafayette County is a county located in the state of Florida. As of 2000, the population was 7,022. It is the second least populated county in the state, having one more resident, according to the 2000 census, than Liberty County, Florida. The U.S. Census Bureau 2005 estimate for the county is...

 counties, near the Suwannee River

Suwannee River

The Suwannee River is a major river of southern Georgia and northern Florida in the United States. It is a wild blackwater river, about long. The Suwannee River is the site of the prehistoric Suwannee Straits which separated peninsular Florida from the panhandle.-Geography:The river rises in the...

. It is 24 miles (38.6 km) long. Near Fletcher, it intersects CR 351, a major access road to Cross City

Cross City, Florida

Cross City is a town in Dixie County, Florida, United States. The population was 1,775 at the 2000 census. As of 2004, the population recorded by the U.S. Census Bureau is 1,800...

 and Horseshoe Beach

Horseshoe Beach, Florida

Horseshoe Beach is a town in Dixie County, Florida, United States. The population was 206 at the 2000 census. As of 2004, the population recorded by the U.S...

. The northern terminus is with an intersection of SR 20

Florida State Road 20

State Road 20 is an east–west route across northern Florida and the Florida Panhandle.-Route description:The western terminus of State Road 20 is at State Road 85 in Niceville. The route proceeds east through Blountstown, crossing the Apalachicola River on the Trammell Bridge, then proceeding...

/US 27near Branford

Branford, Florida

Branford is a town in Suwannee County, Florida, United States. The population was 695 at the 2000 census.-Geography:Branford is located at .The town is located on the banks of the Suwannee River. U.S. Route 27 and U.S...

. The southern terminus of State Road 349 is at an intersection of US 19/ALT US 27/US 98(SR 55

Florida State Road 55

State Road 55 is mainly the internal or secret designation of U.S. Route 19 through Florida, although it has appeared on maps and atlases in several occasions. State Road 55 originates at the Georgia border north of Ashville, and ends at SR 684 in Bradenton. North of Perry, it's the secret route...

) in Old Town

Old Town, Florida

Old Town is an unincorporated community in Dixie County, Florida, United States. It is located at the intersection of US 19/US 98 and State Road 349.-Geography:...

, although it extends southward to Suwannee

Suwannee, Florida

Suwannee is an unincorporated community in Dixie County, Florida, United States. It is located on the Suwannee River near its mouth, at the southern end of the Big Bend region of Florida. It is 23 miles south west of Old Town, to which it is connected by County Road 349.Suwannee is a fishing...

 as County Road 349.

Florida State Road 349 was once US 129 Alternate from 1959 to 1970