Francisco Xavier Castellanos
Encyclopedia
F. Xavier Castellanos, M.D., is currently the Director of Research at the NYU Child Study Center. His work aims at elucidating the neuroscience of ADHD through structural and functional brain imaging studies, collaborating on molecular genetic
studies, and coordinating an interdisciplinary network of translational investigators (the ADHD Neuroscience Network). Dr. Castellanos chaired the NIH ‘Initial Review Group’ (Study Section) on Developmental Psychopathology and Developmental Disabilities from 2005–2007 and is chairing the revision of the diagnostic criteria for externalizing disorders for the forthcoming edition of DSM-V, projected for 2012. He continues to make significant contributions to research into the neurobiological substrates of Attention Deficit Hyperactivity Disorder.
, Spain
on November 16, 1953 to Bolivian parents. When he was four, he, his mother and his two siblings returned to Bolivia
where they lived until he was nine, when the family moved to Washington, D.C. and a year later, to New Orleans, Louisiana
. An avid reader, especially intrigued with science and math, he attended Catholic schools in New Orleans and later received a scholarship to Vassar College
where he became fascinated with the work of Noam Chomsky. At Vassar, he established an independent major in linguistics
and graduated with honors in 1975.
After graduation, working as a professional translator in New Orleans, during which time he translated Jean Piaget
’s Epistemology and Psychology of Functions: Studies in Genetic Epistemology from French to English, Dr. Castellanos began work on a master’s degree in experimental psychology at The University of New Orleans
where he became fascinated by the discovery of endorphins. Following this interest, he applied to and was accepted at The Louisiana State University Medical College at Shreveport. After winning several awards, including the prestigious Chancellor’s Award for Overall Excellence and induction into AOA, the national medical honor society, he graduated in 1986 and continued his medical training at The University of Kentucky
, where he was one of the first graduates of the “Triple Board” program in psychiatry, pediatrics and child psychiatry. During his residency, he won the Abraham Wikler, M.D. Award for Outstanding Psychiatry Resident and was awarded a mini-fellowship in the American Psychiatric Association
's Program for Minority Research Training in Psychiatry.
In 1991, Dr. Castellanos became a Research Fellow in the Child Psychiatry Branch of the National Institute of Mental Health
, where he worked under the supervision of Dr. Judith Rapoport. As a senior staff fellow, he was the head of the ADHD Research Unit and received an award for Excellence in Clinical Care and Research from the National Institute of Mental Health. During this time he also became a fellow in the American Academy of Pediatrics.
In 2001, he left the NIMH to assume the position of Director of Research Training at the New York University Child Study Center
.
Dr. Castellanos is the Brooke and Daniel Neidich Professor of Child and Adolescent Psychiatry at the New York University School of Medicine. He is also the Director of Research at the NYU Child Study Center and the Director of the Phyllis Green and Randolph Cōwen Institute for Pediatric Neuroscience. He is board certified by the American Board of Pediatrics and the American Board of Psychiatry and Neurology in general psychiatry.
Stimulant Drugs and ADHD: Basic and Clinical Neuroscience.
Edited by Mary V. Solanto, Amy F. T. Arnsten and F. Xavier Castellanos. Oct 2000, Oxford University Press.
Castellanos FX, Sonuga-Barke EJ, Milham MP, Tannock R.
Characterizing cognition in ADHD: beyond executive dysfunction.
Trends Cogn Sci. 2006 Mar;10(3):117-23.
Castellanos FX, Sonuga-Barke EJ, Scheres A, Di Martino A, Hyde C, Walters JR.
Varieties of attention-deficit/hyperactivity disorder-related intra-individual variability.
Biol Psychiatry. 2005 Jun 1;57(11):1416-23.
Castellanos FX, Sharp WS, Gottesman RF, Greenstein DK, Giedd JN, Rapoport JL.
Anatomic brain abnormalities in monozygotic twins discordant for attention deficit hyperactivity disorder.
Am J Psychiatry. 2003 Sep;160(9):1693-6.
Castellanos FX, Lee PP, Sharp W, Jeffries NO, Greenstein DK, Clasen LS,
Blumenthal JD, James RS, Ebens CL, Walter JM, Zijdenbos A, Evans AC, Giedd JN,
Rapoport JL.
Developmental trajectories of brain volume abnormalities in children and adolescents with attention-deficit/hyperactivity disorder.
JAMA. 2002 Oct 9;288(14):1740-8.
Castellanos FX, Tannock R.
Neuroscience of attention-deficit/hyperactivity disorder: the search for endophenotypes.
Nat Rev Neurosci. 2002 Aug;3(8):617-28.
Margulies DS, Kelly AMC, Uddin LQ, Biswal BB, Castellanos FX, Milham MP.
Mapping the functional connectivity of anterior cingulate cortex.
Neuroimage. 2007 Aug 15;37(2):579-88.
Castellanos FX, Margulies DS, Kelly C, Uddin LQ, Ghaffari M, Kirsch A, Shaw D,
Shehzad Z, Di Martino A, Biswal B, Sonuga-Barke EJ, Rotrosen J, Adler LA, Milham
MP.
Cingulate-Precuneus Interactions: A New Locus of Dysfunction in Adult Attention-Deficit/Hyperactivity Disorder.
Biol Psychiatry. 2007 Sep 20;
Kelly AMC, Uddin LQ, Biswal BB, Castellanos FX, Milham MP.
Competition between functional brain networks mediates behavioral variability.
Neuroimage. 2007 Aug 23;
Genetics
Genetics , a discipline of biology, is the science of genes, heredity, and variation in living organisms....
studies, and coordinating an interdisciplinary network of translational investigators (the ADHD Neuroscience Network). Dr. Castellanos chaired the NIH ‘Initial Review Group’ (Study Section) on Developmental Psychopathology and Developmental Disabilities from 2005–2007 and is chairing the revision of the diagnostic criteria for externalizing disorders for the forthcoming edition of DSM-V, projected for 2012. He continues to make significant contributions to research into the neurobiological substrates of Attention Deficit Hyperactivity Disorder.
Biography
Francisco Xavier Castellanos was born in MadridMadrid
Madrid is the capital and largest city of Spain. The population of the city is roughly 3.3 million and the entire population of the Madrid metropolitan area is calculated to be 6.271 million. It is the third largest city in the European Union, after London and Berlin, and its metropolitan...
, Spain
Spain
Spain , officially the Kingdom of Spain languages]] under the European Charter for Regional or Minority Languages. In each of these, Spain's official name is as follows:;;;;;;), is a country and member state of the European Union located in southwestern Europe on the Iberian Peninsula...
on November 16, 1953 to Bolivian parents. When he was four, he, his mother and his two siblings returned to Bolivia
Bolivia
Bolivia officially known as Plurinational State of Bolivia , is a landlocked country in central South America. It is the poorest country in South America...
where they lived until he was nine, when the family moved to Washington, D.C. and a year later, to New Orleans, Louisiana
Louisiana
Louisiana is a state located in the southern region of the United States of America. Its capital is Baton Rouge and largest city is New Orleans. Louisiana is the only state in the U.S. with political subdivisions termed parishes, which are local governments equivalent to counties...
. An avid reader, especially intrigued with science and math, he attended Catholic schools in New Orleans and later received a scholarship to Vassar College
Vassar College
Vassar College is a private, coeducational liberal arts college in the town of Poughkeepsie, New York, in the United States. The Vassar campus comprises over and more than 100 buildings, including four National Historic Landmarks, ranging in style from Collegiate Gothic to International,...
where he became fascinated with the work of Noam Chomsky. At Vassar, he established an independent major in linguistics
Linguistics
Linguistics is the scientific study of human language. Linguistics can be broadly broken into three categories or subfields of study: language form, language meaning, and language in context....
and graduated with honors in 1975.
After graduation, working as a professional translator in New Orleans, during which time he translated Jean Piaget
Jean Piaget
Jean Piaget was a French-speaking Swiss developmental psychologist and philosopher known for his epistemological studies with children. His theory of cognitive development and epistemological view are together called "genetic epistemology"....
’s Epistemology and Psychology of Functions: Studies in Genetic Epistemology from French to English, Dr. Castellanos began work on a master’s degree in experimental psychology at The University of New Orleans
University of New Orleans
The University of New Orleans, often referred to locally as UNO, is a medium-sized public urban university located on the New Orleans Lakefront within New Orleans, Louisiana, United States. It is a member of the LSU System and the Urban 13 association. Currently UNO is without a proper chancellor...
where he became fascinated by the discovery of endorphins. Following this interest, he applied to and was accepted at The Louisiana State University Medical College at Shreveport. After winning several awards, including the prestigious Chancellor’s Award for Overall Excellence and induction into AOA, the national medical honor society, he graduated in 1986 and continued his medical training at The University of Kentucky
University of Kentucky
The University of Kentucky, also known as UK, is a public co-educational university and is one of the state's two land-grant universities, located in Lexington, Kentucky...
, where he was one of the first graduates of the “Triple Board” program in psychiatry, pediatrics and child psychiatry. During his residency, he won the Abraham Wikler, M.D. Award for Outstanding Psychiatry Resident and was awarded a mini-fellowship in the American Psychiatric Association
American Psychiatric Association
The American Psychiatric Association is the main professional organization of psychiatrists and trainee psychiatrists in the United States, and the most influential worldwide. Its some 38,000 members are mainly American but some are international...
's Program for Minority Research Training in Psychiatry.
In 1991, Dr. Castellanos became a Research Fellow in the Child Psychiatry Branch of the National Institute of Mental Health
National Institute of Mental Health
The National Institute of Mental Health is one of 27 institutes and centers that make up the National Institutes of Health...
, where he worked under the supervision of Dr. Judith Rapoport. As a senior staff fellow, he was the head of the ADHD Research Unit and received an award for Excellence in Clinical Care and Research from the National Institute of Mental Health. During this time he also became a fellow in the American Academy of Pediatrics.
In 2001, he left the NIMH to assume the position of Director of Research Training at the New York University Child Study Center
NYU Child Study Center
- A new era :The NYU Child Study Center is poised to begin a new and exciting chapter of excellence in cutting-edge care, research and education with the appointment of Glenn Saxe, M.D., as the new chairman of the Department of Child and Adolescent Psychiatry at the NYU School of Medicine and...
.
Dr. Castellanos is the Brooke and Daniel Neidich Professor of Child and Adolescent Psychiatry at the New York University School of Medicine. He is also the Director of Research at the NYU Child Study Center and the Director of the Phyllis Green and Randolph Cōwen Institute for Pediatric Neuroscience. He is board certified by the American Board of Pediatrics and the American Board of Psychiatry and Neurology in general psychiatry.
Select Publications
Stimulant Drugs and ADHDStimulant Drugs and ADHD: Basic and Clinical Neuroscience.
Edited by Mary V. Solanto, Amy F. T. Arnsten and F. Xavier Castellanos. Oct 2000, Oxford University Press.
Castellanos FX, Sonuga-Barke EJ, Milham MP, Tannock R.
Characterizing cognition in ADHD: beyond executive dysfunction.
Trends Cogn Sci. 2006 Mar;10(3):117-23.
Castellanos FX, Sonuga-Barke EJ, Scheres A, Di Martino A, Hyde C, Walters JR.
Varieties of attention-deficit/hyperactivity disorder-related intra-individual variability.
Biol Psychiatry. 2005 Jun 1;57(11):1416-23.
Castellanos FX, Sharp WS, Gottesman RF, Greenstein DK, Giedd JN, Rapoport JL.
Anatomic brain abnormalities in monozygotic twins discordant for attention deficit hyperactivity disorder.
Am J Psychiatry. 2003 Sep;160(9):1693-6.
Castellanos FX, Lee PP, Sharp W, Jeffries NO, Greenstein DK, Clasen LS,
Blumenthal JD, James RS, Ebens CL, Walter JM, Zijdenbos A, Evans AC, Giedd JN,
Rapoport JL.
Developmental trajectories of brain volume abnormalities in children and adolescents with attention-deficit/hyperactivity disorder.
JAMA. 2002 Oct 9;288(14):1740-8.
Castellanos FX, Tannock R.
Neuroscience of attention-deficit/hyperactivity disorder: the search for endophenotypes.
Nat Rev Neurosci. 2002 Aug;3(8):617-28.
Margulies DS, Kelly AMC, Uddin LQ, Biswal BB, Castellanos FX, Milham MP.
Mapping the functional connectivity of anterior cingulate cortex.
Neuroimage. 2007 Aug 15;37(2):579-88.
Castellanos FX, Margulies DS, Kelly C, Uddin LQ, Ghaffari M, Kirsch A, Shaw D,
Shehzad Z, Di Martino A, Biswal B, Sonuga-Barke EJ, Rotrosen J, Adler LA, Milham
MP.
Cingulate-Precuneus Interactions: A New Locus of Dysfunction in Adult Attention-Deficit/Hyperactivity Disorder.
Biol Psychiatry. 2007 Sep 20;
Kelly AMC, Uddin LQ, Biswal BB, Castellanos FX, Milham MP.
Competition between functional brain networks mediates behavioral variability.
Neuroimage. 2007 Aug 23;