Frederick Griffith
Overview
Frederick Griffith was a British bacteriologist whose focus was the epidemiology
and pathology
of bacterial pneumonia
. In January 1928 he reported what is now known as Griffith's Experiment
, the first widely accepted demonstrations of bacterial transformation, whereby a bacterium distinctly changes its form
and function
.
Streptococcus pneumoniae
, known medically as pneumococcus, implicated in most cases of lobar pneumonia
, transformed from one strain into a different strain.
Epidemiology
Epidemiology is the study of health-event, health-characteristic, or health-determinant patterns in a population. It is the cornerstone method of public health research, and helps inform policy decisions and evidence-based medicine by identifying risk factors for disease and targets for preventive...
and pathology
Pathology
Pathology is the precise study and diagnosis of disease. The word pathology is from Ancient Greek , pathos, "feeling, suffering"; and , -logia, "the study of". Pathologization, to pathologize, refers to the process of defining a condition or behavior as pathological, e.g. pathological gambling....
of bacterial pneumonia
Pneumonia
Pneumonia is an inflammatory condition of the lung—especially affecting the microscopic air sacs —associated with fever, chest symptoms, and a lack of air space on a chest X-ray. Pneumonia is typically caused by an infection but there are a number of other causes...
. In January 1928 he reported what is now known as Griffith's Experiment
Griffith's experiment
Griffith's experiment, reported in 1928 by Frederick Griffith, was one of the first experiments suggesting that bacteria are capable of transferring genetic information through a process known as transformation....
, the first widely accepted demonstrations of bacterial transformation, whereby a bacterium distinctly changes its form
Morphology (biology)
In biology, morphology is a branch of bioscience dealing with the study of the form and structure of organisms and their specific structural features....
and function
Physiology
Physiology is the science of the function of living systems. This includes how organisms, organ systems, organs, cells, and bio-molecules carry out the chemical or physical functions that exist in a living system. The highest honor awarded in physiology is the Nobel Prize in Physiology or...
.
Streptococcus pneumoniae
Streptococcus pneumoniae
Streptococcus pneumoniae, or pneumococcus, is Gram-positive, alpha-hemolytic, aerotolerant anaerobic member of the genus Streptococcus. A significant human pathogenic bacterium, S...
, known medically as pneumococcus, implicated in most cases of lobar pneumonia
Lobar pneumonia
Lobar pneumonia is a form of pneumonia that affects a large and continuous area of the lobe of a lung.It is one of the two anatomic classifications of pneumonia .- Symptoms :...
, transformed from one strain into a different strain.
Unanswered Questions