Fresolimumab - AbsoluteAstronomy.com

Fresolimumab is a human

Human

Humans are the only living species in the Homo genus...

monoclonal antibody and an immunomodulator

Immunomodulator

An immunomodulator, also known as an immunotherapy is a substance which has an effect on the immune system.- Immunosuppressants :Inhibits immune response in organ transplantation and autoimmune diseases.- Immunostimulants :...

, developed by Genzyme

Genzyme

Genzyme Corporation is a fully owned subsidiary of Sanofi-Aventis. Before its acquisition, Genzyme was an American biotechnology company based in Cambridge, Massachusetts. In 2010, Genzyme was the world’s third-largest biotechnology company, employing more than 11,000 people around the world...

. It is intended for the treatment of idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis is a chronic, progressive form of lung disease characterized by fibrosis of the supporting framework of the lungs...

(IPF), focal segmental glomerulosclerosis

Focal segmental glomerulosclerosis

Focal segmental glomerulosclerosis is a cause of nephrotic syndrome in children and adolescents, as well as an important cause of kidney failure in adults.It is also known as "focal glomerular sclerosis" or "focal nodular glomerulosclerosis"....

, and cancer

Cancer

Cancer , known medically as a malignant neoplasm, is a large group of different diseases, all involving unregulated cell growth. In cancer, cells divide and grow uncontrollably, forming malignant tumors, and invade nearby parts of the body. The cancer may also spread to more distant parts of the...

.

It binds to and inhibits all isoforms of TGF-β.

it is being tested in humans (clinical trials) against IPF, renal disease, and cancer.

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