GDB Human Genome Database
Encyclopedia
The GDB Human Genome Database was a community curated collection of human genomic data. What set GDB apart from other biological databases was its use of world-class leaders in human genetics to act as curators for the data. In order to ensure a high degree of quality, records within GDB were subjected to a process of peer-review, not unlike a traditional publication. Due to the International collaboration which made up the human genome project, GDB received funding from numerous sources in both Europe and Asia.
provided funding to establish a central repository for human genetic mapping data. This project ultimately resulted in the creation of the GDB Human Genome DataBase in 1990. It was a key database in the Human Genome Project
.
Established under the leadership of Dr.'s Peter Pearson and Dick Lucier, GDB received significant financial support from the US Department of Energy and the National Institutes of Health
. Located at the Johns Hopkins University School of Medicine, GDB became a source of high quality mapping data which were made available both on-line as well as through numerous printed publications.
In 1998, the change of focus in the human genome project redirected funds which were previously available for GDB. However that same year, Dr. A. Jamie Cuticchia
obtained funding from Canadian public and private sources to continue the operations of GDB. While the data curation continued to be performed at Johns Hopkins, GDB central operations were moved to The Hospital for Sick Children in Toronto, Ontario, Canada.
In 2003 RTI International
became the new host for GDB where it continued to be maintained as a public resource for high quality genetic and genomic information.
On June 1, 2008 RTI International shut down GDB operations.
History
In 1989 the Howard Hughes Medical InstituteHoward Hughes Medical Institute
Howard Hughes Medical Institute is a United States non-profit medical research organization based in Chevy Chase, Maryland. It was founded by the American businessman Howard Hughes in 1953. It is one of the largest private funding organizations for biological and medical research in the United...
provided funding to establish a central repository for human genetic mapping data. This project ultimately resulted in the creation of the GDB Human Genome DataBase in 1990. It was a key database in the Human Genome Project
Human Genome Project
The Human Genome Project is an international scientific research project with a primary goal of determining the sequence of chemical base pairs which make up DNA, and of identifying and mapping the approximately 20,000–25,000 genes of the human genome from both a physical and functional...
.
Established under the leadership of Dr.'s Peter Pearson and Dick Lucier, GDB received significant financial support from the US Department of Energy and the National Institutes of Health
National Institutes of Health
The National Institutes of Health are an agency of the United States Department of Health and Human Services and are the primary agency of the United States government responsible for biomedical and health-related research. Its science and engineering counterpart is the National Science Foundation...
. Located at the Johns Hopkins University School of Medicine, GDB became a source of high quality mapping data which were made available both on-line as well as through numerous printed publications.
In 1998, the change of focus in the human genome project redirected funds which were previously available for GDB. However that same year, Dr. A. Jamie Cuticchia
A. Jamie Cuticchia
A. Jamie Cuticchia, Ph.D., J.D. is an American geneticist and bioinformatics scientist with longstanding reputation in the areas of bioinformatics and genomics. In particular, he is was responsible for the collection of the data constituting the human gene map, prior to the final sequencing of the...
obtained funding from Canadian public and private sources to continue the operations of GDB. While the data curation continued to be performed at Johns Hopkins, GDB central operations were moved to The Hospital for Sick Children in Toronto, Ontario, Canada.
In 2003 RTI International
RTI International
RTI International is the trade name of the Research Triangle Institute, an independent research institute established in 1958. The founding tenant of North Carolina’s Research Triangle Park, RTI was created as part of a larger effort to harness the intellectual capital of the area’s three major...
became the new host for GDB where it continued to be maintained as a public resource for high quality genetic and genomic information.
On June 1, 2008 RTI International shut down GDB operations.