GGA2
Encyclopedia
ADP-ribosylation factor-binding protein GGA2 is a protein
that in humans is encoded by the GGA2 gene
.
with RABEP1
, Sortilin 1
, BACE2
and CLINT1
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the GGA2 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
GGA2 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with RABEP1
RABEP1
Rab GTPase-binding effector protein 1 is an enzyme that in humans is encoded by the RABEP1 gene.. It belongs to rabaptin protein family.-Interactions:RABEP1 has been shown to interact with GGA2, RAB4A, RAB5A, AP1G1 and GGA1.-Further reading:...
, Sortilin 1
Sortilin 1
Sortilin is a protein that in humans is encoded by the SORT1 gene. The SORT1 locus shows the strongest association with serum lipoproteins of any genetic locus in the genome. In hepatocytes, sortilin participates in the presecretory degradation of nascent VLDL particles.-Interactions:Sortilin 1 has...
, BACE2
BACE2
Beta-secretase 2 is an enzyme that in humans is encoded by the BACE2 gene.BACE2 is a close homolog of BACE1, a protease known to be an important enzyme involved in the cellular pathways that some believe lead to Alzheimer's disease...
and CLINT1
CLINT1
Clathrin interactor 1 , also known as EPSIN4, is a protein which in humans is encoded by the CLINT1 gene.- Function :The CLINT1 protein binds to the terminal domain of the clathrin heavy chain and stimulates clathrin cage vesicle assembly...
.