GNA12
Encyclopedia
Guanine nucleotide-binding protein subunit alpha-12 is a protein
that in humans is encoded by the GNA12 gene
.
with ARHGEF1
, PPP5C
, ARHGEF12
, Heat shock protein 90kDa alpha (cytosolic), member A1 and TEC
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the GNA12 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
GNA12 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with ARHGEF1
ARHGEF1
Rho guanine nucleotide exchange factor 1 is a protein that in humans is encoded by the ARHGEF1 gene.-Interactions:ARHGEF1 has been shown to interact with GNA13, CD44, P110α and GNA12.-Further reading:...
, PPP5C
PPP5C
Serine/threonine-protein phosphatase 5 is an enzyme that in humans is encoded by the PPP5C gene.-Interactions:PPP5C has been shown to interact with ASK1, CRY2 GNA12. and Rac1,-Further reading:...
, ARHGEF12
ARHGEF12
Rho guanine nucleotide exchange factor 12 is a protein that in humans is encoded by the ARHGEF12 gene.-Interactions:ARHGEF12 has been shown to interact with Insulin-like growth factor 1 receptor, GNA13, PLXNB1, GNA12, TEC and RHOA.-Further reading:...
, Heat shock protein 90kDa alpha (cytosolic), member A1 and TEC
TEC (gene)
Tyrosine-protein kinase Tec is an enzyme that in humans is encoded by the TEC gene.-Interactions:TEC has been shown to interact with GNA12, Janus kinase 2, CD117, Suppressor of cytokine signaling 1, ARHGEF12 and DOK1.-Further reading:...
.
See also
- G12/G13 alpha subunitsG12/G13 alpha subunitsG12/G13 subunits are alpha units of heterotrimeric G proteins that regulate cell processes through the use of guanine nucleotide exchange factors. These two subunits represent a fourth class of G protein alpha subunits. They are not sensitive to pertussis toxin.G proteins G12 and G13 regulate...