GPR177
Encyclopedia
G protein-coupled receptor 177 (GPR177), commonly known as Wntless, is a human gene
that encodes a receptor for Wnt
proteins in Wnt-secreting cells.
Wntless was recently shown to be a cargo for the retromer
complex.
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
that encodes a receptor for Wnt
WNT
WNT is a three-letter abbreviation with multiple meanings, as described below:*Windows NT*WNT *Wnt signaling pathway, a complex protein network...
proteins in Wnt-secreting cells.
Wntless was recently shown to be a cargo for the retromer
Retromer
The retromer is a complex of proteins that has been shown to be important in recycling transmembrane receptors from endosomes to the trans-Golgi network .-Discovery:...
complex.