GTF2H4
Encyclopedia
General transcription factor IIH subunit 4 is a protein
that in humans is encoded by the GTF2H4 gene
.
with MED21
, GTF2F1
, TATA binding protein
, XPB
, POLR2A
and Transcription Factor II B
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the GTF2H4 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
GTF2H4 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with MED21
MED21
Mediator of RNA polymerase II transcription subunit 21 is an enzyme that in humans is encoded by the MED21 gene.-Interactions:MED21 has been shown to interact with Cyclin-dependent kinase 8, BRCA1, GTF2H4, MED6, POLR2A and GTF2F1.-Further reading:...
, GTF2F1
GTF2F1
General transcription factor IIF subunit 1 is a protein that in humans is encoded by the GTF2F1 gene.-Interactions:GTF2F1 has been shown to interact with TAF1, HNRPU, GTF2H4, CTDP1, TATA binding protein, POLR2A, MED21, TAF11, Serum response factor and Transcription Factor II B.-Further reading:...
, TATA binding protein
TATA Binding Protein
The TATA-binding protein is a general transcription factor that binds specifically to a DNA sequence called the TATA box. This DNA sequence is found about 35 base pairs upstream of the transcription start site in some eukaryotic gene promoters...
, XPB
XPB
XPB is an ATP dependent human DNA helicase that is a part of the TFIIH transcription factor complex.-Structure:The 3D structure of the archeael homologue of XPB has been solved by X-ray crystallography by Dr...
, POLR2A
POLR2A
DNA-directed RNA polymerase II subunit RPB1 is an enzyme that in humans is encoded by the POLR2A gene.-Interactions:POLR2A has been shown to interact with Transcription elongation regulator 1, CREB-binding protein, BRCA1, GTF2H4, TATA-binding protein, PCAF, GTF2F1, SUPT5H, Transcription Factor II...
and Transcription Factor II B
Transcription Factor II B
Transcription factor II B is one of several general transcription factors that make up the RNA polymerase II preinitiation complex. It is encoded by the gene....
.