Galactagogue
Encyclopedia
A galactagogue is a substance that promotes lactation
in humans and other animals. It may be synthetic, plant-derived, or endogenous
.
Others include:
Herbal galactogogues are divided into those believed to also have a sedating action on the nursing infant due to their volatile constituents, which can be carried through the breast milk itself, and those seen as promoting milk production without directly affecting the content. This often seems to be linked to anethol content.
Torbangun has been used by the Bataknese
people of Indonesia
as a galactagogue for hundreds of years. An investigation into this traditional usage found that it increased milk volume produced by 65%, compared to 20% for fenugreek
seeds.
. These include domperidone
and metoclopramide
. Domperidone, a dopamine
antagonist
, is not approved for enhanced lactation in the USA. It is, however, prescribed in the UK. Some drugs, primarily atypical antipsychotics such as risperidone
, may cause lactation in both women and men.
Most of those discovered have been found to interact with the dopamine
system in such a way to increase the production of prolactin
endogenously.
Lactation
Lactation describes the secretion of milk from the mammary glands and the period of time that a mother lactates to feed her young. The process occurs in all female mammals, however it predates mammals. In humans the process of feeding milk is called breastfeeding or nursing...
in humans and other animals. It may be synthetic, plant-derived, or endogenous
Endogenous
Endogenous substances are those that originate from within an organism, tissue, or cell. Endogenous retroviruses are caused by ancient infections of germ cells in humans, mammals and other vertebrates...
.
Herbal
The most commonly cited galactagogues are herbal. The most popular of these are:- asparagusAsparagusAsparagus officinalis is a spring vegetable, a flowering perennialplant species in the genus Asparagus. It was once classified in the lily family, like its Allium cousins, onions and garlic, but the Liliaceae have been split and the onion-like plants are now in the family Amaryllidaceae and...
- fenugreekFenugreekFenugreek is a plant in the family Fabaceae. Fenugreek is used both as a herb and as a spice . The leaves and sprouts are also eaten as vegetables...
- brewer's yeast
- blessed thistleCnicusCnicus benedictus , was the sole species in the genus Cnicus, but has been reclassified as Centaurea benedicta...
- alfalfaAlfalfaAlfalfa is a flowering plant in the pea family Fabaceae cultivated as an important forage crop in the US, Canada, Argentina, France, Australia, the Middle East, South Africa, and many other countries. It is known as lucerne in the UK, France, Australia, South Africa and New Zealand, and known as...
Others include:
- aniseAniseAnise , Pimpinella anisum, also called aniseed, is a flowering plant in the family Apiaceae native to the eastern Mediterranean region and Southwest Asia. Its flavor resembles that of liquorice, fennel, and tarragon.- Biology :...
- astragalusAstragalusAstragalus is a large genus of about 3,000 species of herbs and small shrubs, belonging to the legume family Fabaceae, subfamily Faboideae. The genus is native to temperate regions of the Northern Hemisphere...
root - bozaBozaBoza, also bosa , is a popular fermented beverage in Kazakhstan, Turkey, Kyrgyzstan, Albania, Bulgaria, Macedonia, Montenegro, Bosnia and Herzegovina, parts of Romania, Serbia, Ukraine and also Poland and Lithuania...
- burdockBurdockBurdock is any of a group of biennial thistles in the genus Arctium, family Asteraceae. Native to the Old World, several species have been widely introduced worldwide....
- nettleNettleNettles constitute between 24 and 39 species of flowering plants of the genus Urtica in the family Urticaceae, with a cosmopolitan though mainly temperate distribution. They are mostly herbaceous perennial plants, but some are annual and a few are shrubby...
- fennelFennelFennel is a plant species in the genus Foeniculum . It is a member of the family Apiaceae . It is a hardy, perennial, umbelliferous herb, with yellow flowers and feathery leaves...
- flaxFlaxFlax is a member of the genus Linum in the family Linaceae. It is native to the region extending from the eastern Mediterranean to India and was probably first domesticated in the Fertile Crescent...
- oatmealOatmealOatmeal is ground oat groats , or a porridge made from oats . Oatmeal can also be ground oat, steel-cut oats, crushed oats, or rolled oats....
- quinoaQuinoaQuinoa , a species of goosefoot , is a grain-like crop grown primarily for its edible seeds. It is a pseudocereal rather than a true cereal, or grain, as it is not a member of the grass family...
- soapwortSoapwortCommon Soapwort is a vespertine flower, and a common perennial plant from the carnation family . Other common names are Bouncing Bet and Sweet William; locally it is simply "the Soapwort" although there are about 20 species of soapworts altogether.The scientific name Saponaria is derived from the...
- vervain
- red raspberry leafRed raspberry leafThe red raspberry leaf is a pale-green leaf produced by the raspberry plant; an upright shrub with perennial roots and prickly, biennial canes. The leaf has been used in folk remedies, due to its rich content in vitamins, minerals, and tannins.-Pregnancy:Traditional lore suggests that pregnant...
- marshmallowAlthaea (genus)Althaea is a genus of 6-12 species of perennial herbs native to Europe and western Asia. It includes Althaea officinalis, also known as the marshmallow plant, whence the fluffy confection got its name. They are found on the banks of rivers and in salt marshes, preferring moist, sandy soils. The...
(althaea) root - Torbangun
Herbal galactogogues are divided into those believed to also have a sedating action on the nursing infant due to their volatile constituents, which can be carried through the breast milk itself, and those seen as promoting milk production without directly affecting the content. This often seems to be linked to anethol content.
Torbangun has been used by the Bataknese
Batak (Indonesia)
Batak is a collective term used to identify a number of ethnic groups predominantly found in North Sumatra, Indonesia. The term is used to include the Toba, Karo, Pakpak, Simalungun, Angkola and Mandailing, each of which are distinct but related groups with distinct, albeit related, languages and...
people of Indonesia
Indonesia
Indonesia , officially the Republic of Indonesia , is a country in Southeast Asia and Oceania. Indonesia is an archipelago comprising approximately 13,000 islands. It has 33 provinces with over 238 million people, and is the world's fourth most populous country. Indonesia is a republic, with an...
as a galactagogue for hundreds of years. An investigation into this traditional usage found that it increased milk volume produced by 65%, compared to 20% for fenugreek
Fenugreek
Fenugreek is a plant in the family Fabaceae. Fenugreek is used both as a herb and as a spice . The leaves and sprouts are also eaten as vegetables...
seeds.
Pharmaceutical
The most effective galactagogues are medications, available usually by medical prescriptionMedical prescription
A prescription is a health-care program implemented by a physician or other medical practitioner in the form of instructions that govern the plan of care for an individual patient. Prescriptions may include orders to be performed by a patient, caretaker, nurse, pharmacist or other therapist....
. These include domperidone
Domperidone
Domperidone is an antidopaminergic drug, developed by Janssen Pharmaceutica, and used orally, rectally or intravenously, generally to suppress nausea and vomiting, or as a prokinetic agent...
and metoclopramide
Metoclopramide
Metoclopramide is an antiemetic and gastroprokinetic agent. It is commonly used to treat nausea and vomiting, to facilitate gastric emptying in people with gastroparesis, and as a treatment for the gastric stasis often associated with migraine headaches.-Medical uses:Metoclopramide is commonly...
. Domperidone, a dopamine
Dopamine
Dopamine is a catecholamine neurotransmitter present in a wide variety of animals, including both vertebrates and invertebrates. In the brain, this substituted phenethylamine functions as a neurotransmitter, activating the five known types of dopamine receptors—D1, D2, D3, D4, and D5—and their...
antagonist
Antagonist
An antagonist is a character, group of characters, or institution, that represents the opposition against which the protagonist must contend...
, is not approved for enhanced lactation in the USA. It is, however, prescribed in the UK. Some drugs, primarily atypical antipsychotics such as risperidone
Risperidone
Risperidone is a second generation or atypical antipsychotic, sold under the trade name . It is used to treat schizophrenia , schizoaffective disorder, the mixed and manic states associated with bipolar disorder, and irritability in people with autism...
, may cause lactation in both women and men.
Most of those discovered have been found to interact with the dopamine
Dopamine
Dopamine is a catecholamine neurotransmitter present in a wide variety of animals, including both vertebrates and invertebrates. In the brain, this substituted phenethylamine functions as a neurotransmitter, activating the five known types of dopamine receptors—D1, D2, D3, D4, and D5—and their...
system in such a way to increase the production of prolactin
Prolactin
Prolactin also known as luteotropic hormone is a protein that in humans is encoded by the PRL gene.Prolactin is a peptide hormone discovered by Henry Friesen...
endogenously.
Further Reading
- Diana WestDiana West (lactation consultant)Diana West is a leading lactation consultant and noted author in the field of breastfeeding.-Biography:Diana West was born August 8, 1965 in Rogers, Arkansas. West is the granddaughter of Clyde T...
and L. Marasco, The Breastfeeding Mother's Guide to Making More Milk. New York: McGraw-Hill, 2008.