Gelclair
Encyclopedia
Gelclair is an oral gel that coats the surface of the mouth forming a thin protective film over painful oral lesions, such as those caused by radiotherapy or chemotherapy
treatment for cancer
.
usually caused by radiotherapy or chemotherapy
treatment for cancer
but can also be caused by medication, disease, oral surgery, stress, traumatic ulcers caused by dental braces and dentures and ageing.
Gelclair can be used by patients of all ages.
Gelclair is usually used 3 times a day or as needed. It is usually diluted with water and rinsed around the mouth. It can be used undiluted where no water is available, applied directly.
Gelclair does not numb the mouth and can be used in conjunction with other treatment options for managing oral mucositis, including antibacterial mouthwashes and painkillers.
De Cordi et al. studied thirty patients with lesions of the mouth and oropharynx (caused by various diseases). 83% of patients reported a reduction in pain, 13% remained the same and 3% showed initial improvement but then got worse. 83% showed a distinct improvement in functionality in the ability to take food, 7% remained the same, and 7% got worse, while 3% reported considerable improvement followed by slight worsening. 57% of patients reported an improvement in the grade of oral mucositis, 40% remained the same while 3% got worse.
Berndtson studied ten patients who were given Gelclair to evaluate its effect on their symptoms of oral mucositis. All reported that the product was acceptable for its taste and consistency, and a palliative soothing effect was noted.
Chemotherapy
Chemotherapy is the treatment of cancer with an antineoplastic drug or with a combination of such drugs into a standardized treatment regimen....
treatment for cancer
Cancer
Cancer , known medically as a malignant neoplasm, is a large group of different diseases, all involving unregulated cell growth. In cancer, cells divide and grow uncontrollably, forming malignant tumors, and invade nearby parts of the body. The cancer may also spread to more distant parts of the...
.
Uses
Gelclair can be used in the management of the painful symptoms of oral mucositisMucositis
Mucositis is the painful inflammation and ulceration of the mucous membranes lining the digestive tract, usually as an adverse effect of chemotherapy and radiotherapy treatment for cancer. Mucositis can occur anywhere along the gastrointestinal tract, but oral mucositis refers to the particular...
usually caused by radiotherapy or chemotherapy
Chemotherapy
Chemotherapy is the treatment of cancer with an antineoplastic drug or with a combination of such drugs into a standardized treatment regimen....
treatment for cancer
Cancer
Cancer , known medically as a malignant neoplasm, is a large group of different diseases, all involving unregulated cell growth. In cancer, cells divide and grow uncontrollably, forming malignant tumors, and invade nearby parts of the body. The cancer may also spread to more distant parts of the...
but can also be caused by medication, disease, oral surgery, stress, traumatic ulcers caused by dental braces and dentures and ageing.
Gelclair can be used by patients of all ages.
Gelclair is usually used 3 times a day or as needed. It is usually diluted with water and rinsed around the mouth. It can be used undiluted where no water is available, applied directly.
Gelclair does not numb the mouth and can be used in conjunction with other treatment options for managing oral mucositis, including antibacterial mouthwashes and painkillers.
Clinical Evidence
Innocenti et al. studied Gelclair in a total of thirty patients with chemotherapy-induced oral lesions. Results showed a 92% reduction in mean pain scores 5–7 hours after the first administration of Gelclair. Patients were also given Gelclair for a further 7–10 days and at the end of this period, pain scores were recorded. After one week of using Gelclair, 87% of patients reported overall improvements relating to pain on swallowing food, liquids and saliva.De Cordi et al. studied thirty patients with lesions of the mouth and oropharynx (caused by various diseases). 83% of patients reported a reduction in pain, 13% remained the same and 3% showed initial improvement but then got worse. 83% showed a distinct improvement in functionality in the ability to take food, 7% remained the same, and 7% got worse, while 3% reported considerable improvement followed by slight worsening. 57% of patients reported an improvement in the grade of oral mucositis, 40% remained the same while 3% got worse.
Berndtson studied ten patients who were given Gelclair to evaluate its effect on their symptoms of oral mucositis. All reported that the product was acceptable for its taste and consistency, and a palliative soothing effect was noted.