The Glucommander is a computer-directed method of inpatient glucose management shown to be safe, simple, and effective. The software concept originated from an article published in 1982 by White et al. That article presented a complex set of orders for determining the basal insulin requirements in pediatric patients using an insulin pump

Insulin pump

The insulin pump is a medical device used for the administration of insulin in the treatment of diabetes mellitus, also known as continuous subcutaneous insulin infusion therapy.The device includes:...

.

When data were graphed, it was obvious that a linear regression

Linear regression

In statistics, linear regression is an approach to modeling the relationship between a scalar variable y and one or more explanatory variables denoted X. The case of one explanatory variable is called simple regression...

 with an intercept of 60 and a slope, or multiplier, of 0.02 could resolve the complexity of the orders of White et al. to a single formula for calculation of intravenous insulin requirements: (blood glucose − 60) × 0.02 = insulin dose/h. Incorporated into a bedside laptop computer system by Atlanta Diabetes Associates (Paul Davidson, M.D., Bruce Bode

Bruce Bode

Bruce Bode, MD, FACE is a diabetes specialist with the Atlanta Diabetes Associates in Atlanta, GA and is a clinical associate professor at Emory University in the Department of Medicine. He has served on the board of directors of the Atlanta chapters of the Juvenile Diabetes Research Foundation ,...

, M.D., and Dennis Steed, M.D.), the Glucommander concept was later enhanced and commercialized into the Glucommander Plus product by Glytcec.

Davidson and Bode now serve as medical advisors to Glytec LLC, which manufactures the Glucommander. The company initially received clearance from U.S. Food and Drug Administration

Food and Drug Administration

The Food and Drug Administration is an agency of the United States Department of Health and Human Services, one of the United States federal executive departments...

(FDA)in June 2006, and again in 2010 for an Enterprise version of the software.

Indications for use

The Glucommander is intended to evaluate the current and cumulative patient blood glucose values, and, based on the aggregate of those measurements, whether one or many, regulate the infusion of I.V. fluids, through an I.V. infusion pump, and drive the blood glucose level towards a predetermined target range. Once that target blood glucose range has been reached, the system's function is to recommend a titration of insulin, glucose, and saline for the purpose of maintaining the patient's blood glucose level in that target range. The system is programmed to provide intravenous dosing of glucose, saline, and insulin, as well as subcutaneous dosing of glucose and insulin.

External links

• http://care.diabetesjournals.org/content/28/10/2418.full.pdf
• http://www.redmondregional.com/CPM/Routine%20Glucommander%20Orders.pdf
• http://www.criticalcarecanada.com/abstracts/glucommander-method.pdf
• http://www.adaendo.com/GAAACE/GaAACECVProtocol.pdf
• http://www.accessdata.fda.gov/cdrh_docs/pdf10/K101344.pdf
• http://www.accessdata.fda.gov/cdrh_docs/pdf6/K061110.pdf
• http://www.glytecsystems.com/news/West_Tennessee_Healthcare_Accelerates_Optimum_Inpatient_Glucose_Control_with_Glucommander_Plus.aspx
• http://www.mosescone.com/documents/public/Nursing%20Beat/NB2_06.pdf
• http://resources.aace.com/PDF/ID=20%20Pharmacy%20Medications%20References/Davidson_JDiabetesSciTechnol_2008.PDF
• http://www.utswanesthesia.com/education/images/stories/PDF%20Documents/Perioperative_Management_of_the_Diabetic_Patient_EMedicine.pdf
• http://www.glytecsystems.com/news/Glucotec_partners_with_cardinal_health_for_insulin_therapy_with_alaris_system.aspx
• http://www.journalofdst.com/January2009/pdf/abstract/VOL-3-1-ORG6-STEIL-ABSTRACT.pdf
• http://www.journalofdst.org/Journal/pdf/November2007/VOL-1-6-SYM2-BEQUETTE.pdf
• http://www.wichtig-publisher.com/ntm/subs2009/vol.%2027%20no.%201%202009/33-38%20Singer.pdf