Govindarajan Padmanabhan
Encyclopedia
Govindarajan Padmanaban (Malayalam:ഗോവിന്ദരാജന്‍ പദ്മനാഭന്‍) (born 20 March 1938) is a renowned biochemist
Biochemistry
Biochemistry, sometimes called biological chemistry, is the study of chemical processes in living organisms, including, but not limited to, living matter. Biochemistry governs all living organisms and living processes...

 and a pioneer in Indian biotechnology. He was former director of the Indian Institute of Science
Indian Institute of Science
Indian Institute of Science is a research institution of higher learning located in Bangalore, India. It was established in 1909.-History:After a chance meeting between Jamsetji N...

 (IISc) and presently serving as honorary professor in the department of biochemistry, IISc.

Early life and education

Padmanaban was brought up in a family of engineers. His parents belonged to Tanjore district of Tamil Nadu
Tamil Nadu
Tamil Nadu is one of the 28 states of India. Its capital and largest city is Chennai. Tamil Nadu lies in the southernmost part of the Indian Peninsula and is bordered by the union territory of Pondicherry, and the states of Kerala, Karnataka, and Andhra Pradesh...

 but had settled in Bangalore. After completing his schooling in Bangalore, he joined an Engineering College. However, he found engineering uninteresting, and he joined the Presidency College in Chennai
Chennai
Chennai , formerly known as Madras or Madarasapatinam , is the capital city of the Indian state of Tamil Nadu, located on the Coromandel Coast off the Bay of Bengal. Chennai is the fourth most populous metropolitan area and the sixth most populous city in India...

 to complete a bachelors degree in chemistry. He completed his masters in Soil Chemistry at Indian Agricultural Research Institute
Indian Agricultural Research Institute
The Indian Agricultural Research Institute is India's premier national Institute for agricultural research, education and extension. It has served the cause of science and society with distinction through first rate research, generation of appropriate technologies and development of human resources...

, New Delhi
New Delhi
New Delhi is the capital city of India. It serves as the centre of the Government of India and the Government of the National Capital Territory of Delhi. New Delhi is situated within the metropolis of Delhi. It is one of the nine districts of Delhi Union Territory. The total area of the city is...

 and Ph.D. in Biochemistry at the Indian Institute of science IISc, Bangalore
Bangalore
Bengaluru , formerly called Bengaluru is the capital of the Indian state of Karnataka. Bangalore is nicknamed the Garden City and was once called a pensioner's paradise. Located on the Deccan Plateau in the south-eastern part of Karnataka, Bangalore is India's third most populous city and...

 in 1966.

Research

In the early years of his research, he primarily worked in the transcriptional regulation of Eukaryotic genes in the liver. He was interested in elucidating the multifaceted role of heme in cellular processes. His group discovered the heme-biosynthetic pathway in the malarial parasite and showed it to be a drug target. He has also been interested in the area of vaccine development. His team was successful in showing the antimalarial property of Curcumin
Curcumin
Curcumin is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family . The other two curcuminoids are desmethoxycurcumin and bis-desmethoxycurcumin. The curcuminoids are natural phenols and are responsible for the yellow color of turmeric...

 and its efficacy in combination therapy in 2004.

Awards

  • Shanti Swarup Bhatnagar Prize for Science and Technology (1983)
  • Padma Shri
    Padma Shri
    Padma Shri is the fourth highest civilian award in the Republic of India, after the Bharat Ratna, the Padma Vibhushan and the Padma Bhushan...

     (1991)
  • Padma Bhushan
    Padma Bhushan
    The Padma Bhushan is the third highest civilian award in the Republic of India, after the Bharat Ratna and the Padma Vibhushan, but comes before the Padma Shri. It is awarded by the Government of India.-History:...

    (2003)
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