Guided rat
Encyclopedia
A remotely-guided rat, popularly called a ratbot or robo-rat, is a rat
Rat
Rats are various medium-sized, long-tailed rodents of the superfamily Muroidea. "True rats" are members of the genus Rattus, the most important of which to humans are the black rat, Rattus rattus, and the brown rat, Rattus norvegicus...

 with electrodes implanted in the medial forebrain bundle
Medial forebrain bundle
The Medial forebrain bundle , is a complex bundle of axons coming from the basal olfactory regions, the periamygdaloid region, and the septal nuclei.-Anatomy:...

 (MFB) and sensorimotor cortex of its brain. They were developed in 2002 by Sanjiv Talwar and John Chapin at the State University of New York Downstate Medical Center
SUNY Downstate Medical Center
The State University of New York Health Science Center at Brooklyn, better known as SUNY Downstate Medical Center, is a public university and medical center located in central Brooklyn, New York and the only academic center for health education, research, and patient care serving Brooklyn’s 2.5...

. The rats wear a small electronics backpack containing a radio receiver and electrical stimulator. The rat receives remote stimulation in the sensorimotor cortex via its backpack that causes the rat to feel a sensation in its left or right whiskers
Vibrissae
Vibrissae , or whiskers, are specialized hairs usually employed for tactile sensation. The term may also refer to the thick hairs found inside human nostrils, but these have no sensorial function and only operate as an airborne particulate barrier...

, and stimulation in the MFB that is interpreted as a reward
Reward system
In neuroscience, the reward system is a collection of brain structures which attempts to regulate and control behavior by inducing pleasurable effects...

 or pleasure.

After a period of training and conditioning
Physical exercise
Physical exercise is any bodily activity that enhances or maintains physical fitness and overall health and wellness. It is performed for various reasons including strengthening muscles and the cardiovascular system, honing athletic skills, weight loss or maintenance, as well as for the purpose of...

 using MFB stimulation as a reward, the rats can be remotely directed to move left, right, and forward in response to whisker stimulation signals. It is possible to roughly guide the animal along an obstacle course, jumping small gaps and scaling obstacles.

Applications

Currently, robo-rats are primarily being trained to detect explosives in areas where humans and existing robots cannot efficiently search, such as crowds and cargo ships. Other possible uses of the robo-rat include search and rescue
Search and rescue
Search and rescue is the search for and provision of aid to people who are in distress or imminent danger.The general field of search and rescue includes many specialty sub-fields, mostly based upon terrain considerations...

 operations following a natural disaster, military reconnaissance and landmine detection. A camera, transmitter, and GPS
Global Positioning System
The Global Positioning System is a space-based global navigation satellite system that provides location and time information in all weather, anywhere on or near the Earth, where there is an unobstructed line of sight to four or more GPS satellites...

 receiver that mount on rat backpacks have been designed to facilitate these purposes. However, it has been suggested that by interpreting biological signals directly from the brain of the rat, additional information could be obtained without the use of external equipment. This could be used, for example, to detect chemical and biological toxins in the air via the rat's own sense of smell.

Additionally, these rats have further applications in pure science. It serves as a new experimental model for behavioral studies in psychology
Psychology
Psychology is the study of the mind and behavior. Its immediate goal is to understand individuals and groups by both establishing general principles and researching specific cases. For many, the ultimate goal of psychology is to benefit society...

. MFB stimulation is a valuable tool in behavioral research, but traditional research using MFB stimulation has required that test animals be confined within an experimental chamber. This difficulty is avoided because the robo-rat can be guided wirelessly.

Principal funding for the development of the robo-rat has come from DARPA
Defense Advanced Research Projects Agency
The Defense Advanced Research Projects Agency is an agency of the United States Department of Defense responsible for the development of new technology for use by the military...

.

Ethics

Concerns have been raised by animal rights groups about the use of animals in this context, particularly due to a concern about the removal of autonomy from an independent creature. For example, a spokesman of the Dr Hadwen Trust
Dr Hadwen Trust
The Dr Hadwen Trust is the UK's leading medical research charity that funds and promotes exclusively non-animal techniques to replace animal experiments...

, a group funding alternatives to animal research in medicine, has said that the experiments are an "appalling example of how the human species instrumentalizes other species."

Researchers tend to liken the training mechanism of the robo-rat to standard operant conditioning
Operant conditioning
Operant conditioning is a form of psychological learning during which an individual modifies the occurrence and form of its own behavior due to the association of the behavior with a stimulus...

 techniques. Talwar himself has acknowledged the ethical issues apparent in the development of the robo-rat, but points out that the research meets standards for animal treatment laid down by the National Institute of Health. Moreover, the researchers emphasize that the animals are trained, not coerced, into particular behaviors. Because the rats are encouraged to act via the reward of pleasure, not muscularly compelled to behave in a particular manner, their behavior under MFB stimulation is likened to a carrot-and-stick model of encouraged behavior versus a system of mind control
Mind control
Mind control refers to a process in which a group or individual "systematically uses unethically manipulative methods to persuade others to conform to the wishes of the manipulator, often to the detriment of the person being manipulated"...

. It seems unlikely that the rats could be persuaded to knowingly risk their lives even with this stimulation. "Our animals were completely happy and treated well," Talwar stated.

The technology is reminiscent of experiments performed in 1965 by Dr Jose Delgado
José Manuel Rodriguez Delgado
José Manuel Rodriguez Delgado was a Spanish professor of physiology at Yale University, famed for his research into mind control through electrical stimulation of regions in the brain.-Biography:...

, a controversial scientist who was able to pacify a charging bull via electrodes fitted in its brain. He was also said to control cats and monkeys like "electronic toys." Extension of the current work to higher animals is unlikely to occur, simply for ethical reasons.

External links

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