HIV gag stem loop 3 (GSL3)
Encyclopedia
HIV gag stem loop 3 is an RNA element
that is known to direct specific packaging of HIV
-1 genomic RNA
. Deletion of GSL3 leads to decreases in both viral RNA packaging and dimerisation.
Cis-regulatory element
A cis-regulatory element or cis-element is a region of DNA or RNA that regulates the expression of genes located on that same molecule of DNA . This term is constructed from the Latin word cis, which means "on the same side as". These cis-regulatory elements are often binding sites for one or...
that is known to direct specific packaging of HIV
HIV
Human immunodeficiency virus is a lentivirus that causes acquired immunodeficiency syndrome , a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive...
-1 genomic RNA
Genome
In modern molecular biology and genetics, the genome is the entirety of an organism's hereditary information. It is encoded either in DNA or, for many types of virus, in RNA. The genome includes both the genes and the non-coding sequences of the DNA/RNA....
. Deletion of GSL3 leads to decreases in both viral RNA packaging and dimerisation.