HLA-DO
Encyclopedia
HLA-DO is a dimeric protein
composed of α-
and β
-subunits which assists in the down-regulation of HLA-DM
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
composed of α-
HLA-DOA
HLA class II histocompatibility antigen, DO alpha chain is a protein that in humans is encoded by the HLA-DOA gene.-Further reading:...
and β
HLA-DOB
HLA class II histocompatibility antigen, DO beta chain is a protein that in humans is encoded by the HLA-DOB gene.-Further reading:...
-subunits which assists in the down-regulation of HLA-DM
HLA-DM
HLA-DM is an intracellular protein involved in peptide presentation by MHC class II. It is encoded by the genes and .In the endosomes, HLA-DM functions by promoting the dissociation of the CLIP peptide from MHC class II which allows endosomal peptides to bind...
.