Haementeria ghilianii, also known as the Giant Amazon Leech, is one the world's largest species of leech. It can grow to be 450 millimetres (17.7 inches) in length and 100 millimetres (3.9 inches) in width. At adulthood, these leeches are a greyish brown colour, as opposed to while juvenile, when they do not have uniform colour, but rather, a noncontinuous stripe of colour, and patched colouring. They live from the Guianas to the Amazon. The leech produces the anticoagulant

Anticoagulant

An anticoagulant is a substance that prevents coagulation of blood. A group of pharmaceuticals called anticoagulants can be used in vivo as a medication for thrombotic disorders. Some anticoagulants are used in medical equipment, such as test tubes, blood transfusion bags, and renal dialysis...

 protease

Protease

A protease is any enzyme that conducts proteolysis, that is, begins protein catabolism by hydrolysis of the peptide bonds that link amino acids together in the polypeptide chain forming the protein....

 Hementin

Hementin

Hementin is an anticoagulant protease from the salivary glands of the giant Amazon leech . Hementin dissolves a type of platelet rich blood clot which cannot be dissolved by other well used drugs like streptokinase and urokinase....

from its salivary glands.