Hans Gruneberg
Encyclopedia
Hans Grüneberg, also written as Hans Grueneberg and Hans Gruneberg, (26 May 1907–23 October 1982) was a British
geneticist
. Grüneberg was born in Wuppertal
–Elberfeld
in Germany. He obtained an MD
from the University of Bonn
, a PhD
in biology from the University of Berlin and a DSc
from the University of London
. He arrived in London in 1933, at the invitation of J.B.S. Haldane and Sir Henry Dale.
He was elected a Fellow of the Royal Society in 1956. Most of his work focused on mouse genetics, in which his speciality was the study of pleiotropic effects of mutation
s on the development of the mouse skeleton.
He was the first person to describe siderocytes and sideroblasts, atypical nucleated erythrocytes with granules of iron accumulated in perinuclear mitochondria. This he reported in two letters to the journal Nature
in 1941.
Great Britain
Great Britain or Britain is an island situated to the northwest of Continental Europe. It is the ninth largest island in the world, and the largest European island, as well as the largest of the British Isles...
geneticist
Genetics
Genetics , a discipline of biology, is the science of genes, heredity, and variation in living organisms....
. Grüneberg was born in Wuppertal
Wuppertal
Wuppertal is a city in North Rhine-Westphalia, Germany. It is located in and around the Wupper river valley, and is situated east of the city of Düsseldorf and south of the Ruhr area. With a population of approximately 350,000, it is the largest city in the Bergisches Land...
–Elberfeld
Elberfeld
Elberfeld is a municipal subdivision of the German city of Wuppertal; it was an independent town until 1929.-History:The first official mentioning of the geographic area on the banks of today's Wupper River as "elverfelde" was in a document of 1161...
in Germany. He obtained an MD
Doctor of Medicine
Doctor of Medicine is a doctoral degree for physicians. The degree is granted by medical schools...
from the University of Bonn
University of Bonn
The University of Bonn is a public research university located in Bonn, Germany. Founded in its present form in 1818, as the linear successor of earlier academic institutions, the University of Bonn is today one of the leading universities in Germany. The University of Bonn offers a large number...
, a PhD
PHD
PHD may refer to:*Ph.D., a doctorate of philosophy*Ph.D. , a 1980s British group*PHD finger, a protein sequence*PHD Mountain Software, an outdoor clothing and equipment company*PhD Docbook renderer, an XML renderer...
in biology from the University of Berlin and a DSc
DSC
-in academia:* D.Sc., Doctor of Science* Doctor of Surgical Chiropody, superseded in the 1960s by Doctor of Podiatric Medicine* Dalton State College, Georgia* Daytona State College, Florida* Deep Springs College, California* Dixie State College of Utah...
from the University of London
University of London
-20th century:Shortly after 6 Burlington Gardens was vacated, the University went through a period of rapid expansion. Bedford College, Royal Holloway and the London School of Economics all joined in 1900, Regent's Park College, which had affiliated in 1841 became an official divinity school of the...
. He arrived in London in 1933, at the invitation of J.B.S. Haldane and Sir Henry Dale.
He was elected a Fellow of the Royal Society in 1956. Most of his work focused on mouse genetics, in which his speciality was the study of pleiotropic effects of mutation
Mutation
In molecular biology and genetics, mutations are changes in a genomic sequence: the DNA sequence of a cell's genome or the DNA or RNA sequence of a virus. They can be defined as sudden and spontaneous changes in the cell. Mutations are caused by radiation, viruses, transposons and mutagenic...
s on the development of the mouse skeleton.
He was the first person to describe siderocytes and sideroblasts, atypical nucleated erythrocytes with granules of iron accumulated in perinuclear mitochondria. This he reported in two letters to the journal Nature
Nature (journal)
Nature, first published on 4 November 1869, is ranked the world's most cited interdisciplinary scientific journal by the Science Edition of the 2010 Journal Citation Reports...
in 1941.
Career
- Honorary Research Assistant, University College LondonUniversity College LondonUniversity College London is a public research university located in London, United Kingdom and the oldest and largest constituent college of the federal University of London...
, 1933–38 - Moseley Research Student of Royal Society, 1938–42
- Captain, Royal Army Medical CorpsRoyal Army Medical CorpsThe Royal Army Medical Corps is a specialist corps in the British Army which provides medical services to all British Army personnel and their families in war and in peace...
, 1942–46 - Reader in Genetics, University College London, 1946–55
- Honorary Director of the Medical Research Council Experimental Genetics Unit at University College London, 1955–1972
- Professor of Genetics University College London, 1956–1974
- Affiliated with the Department of Pathology, Mount Vernon Hospital, Northwood, Middlesex
- Emeritus Professor University College London, from retirement, 1974
Books
- 1947. Animal genetics and medicine. Hamish Hamilton, London.
- 1952. The genetics of the mouse. 2nd ed, revised and enlarged. Nijhoff, The Hague.
- 1963. The pathology of development: a study of inherited skeletal disorders in animals. Wiley, London.
See also
- Grüneberg ganglionGrüneberg ganglionThe Grüneberg ganglion, also written as Grueneberg ganglion and Gruneberg ganglion, is an olfactory ganglion at the entrance of the nose of mammals that is involved in the detection of alarm pheromones and cold temperatures...
, an olfactory ganglion in rodents first described by Hans Grueneberg in 1973