Henry Kronenberg is an American physician and academic. he is Division Head of Endocrinology at the Massachusetts General Hospital

Massachusetts General Hospital

Massachusetts General Hospital is a teaching hospital and biomedical research facility in the West End neighborhood of Boston, Massachusetts...

 in Boston

Boston

Boston is the capital of and largest city in Massachusetts, and is one of the oldest cities in the United States. The largest city in New England, Boston is regarded as the unofficial "Capital of New England" for its economic and cultural impact on the entire New England region. The city proper had...

, MA and a Professor of Medicine at the Harvard Medical School

Harvard Medical School

Harvard Medical School is the graduate medical school of Harvard University. It is located in the Longwood Medical Area of the Mission Hill neighborhood of Boston, Massachusetts....

. He is noted for his work on parathyroid hormone and the use of genetic mouse models to understand the role of parathyroid hormone

Parathyroid hormone

Parathyroid hormone , parathormone or parathyrin, is secreted by the chief cells of the parathyroid glands as a polypeptide containing 84 amino acids...

 and parathyroid hormone-related protein

Parathyroid hormone-related protein

Parathyroid hormone-related protein is a protein member of the parathyroid hormone family. It is occasionally secreted by cancer cells . However, it also has normal functions.- Function :PTHrP acts as an endocrine, autocrine, paracrine, and intracrine hormone...

 in the regulation of bone

Bone

Bones are rigid organs that constitute part of the endoskeleton of vertebrates. They support, and protect the various organs of the body, produce red and white blood cells and store minerals. Bone tissue is a type of dense connective tissue...

 formation and remodeling.

Accomplishments

Dr. Kronenberg has made a series of fundamental observations of importance to the understanding of how several peptides regulate the formation and remodeling of bone. These include the cloning of a cDNA for parathyroid hormone

Parathyroid hormone

Parathyroid hormone , parathormone or parathyrin, is secreted by the chief cells of the parathyroid glands as a polypeptide containing 84 amino acids...

, the identification of a role for parathyroid hormone-related protein

Parathyroid hormone-related protein

Parathyroid hormone-related protein is a protein member of the parathyroid hormone family. It is occasionally secreted by cancer cells . However, it also has normal functions.- Function :PTHrP acts as an endocrine, autocrine, paracrine, and intracrine hormone...

 in endochondral ossification

Endochondral ossification

Endochondral ossification is one of the two essential processes during fetal development of the mammalian skeletal system by which bone tissue is created. Unlike intramembranous ossification, which is the other process by which bone tissue is created, cartilage is present during endochondral...

 through indian hedgehog (IHH

IHH

Indian hedgehog homolog , also known as IHH, is a protein which in humans is encoded by the IHH gene.-Function:The Indian Hedgehog protein is one of three proteins in the mammalian hedgehog family, the others being desert hedgehog and Sonic hedgehog...

) activation, and studies that identified a role for parathyroid hormone in the regulation of the bone marrow stem cell niche.

He has served as the President of the American Society for Bone and Mineral Research. He is currently a member of the Board of Advisors of the Rolanette and Berdon Lawrence Bone Disease Program of Texas

Bone Disease Program of Texas

- Description and History :The Rolanette and Berdon Lawrence Bone Disease Program of Texas is a collaborative program between the Baylor College of Medicine and the University of Texas M.D. Anderson Cancer Center. It was established by an initial endowment to the two institutions by Rolanette and...

.