Hepatoprotection
Encyclopedia
Hepatoprotection or antihepatotoxicity is the ability to prevent damage to the liver
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An example of a hepatoprotective medicine is silibinin
, derived from Milk Thistle
, which selectively inhibits leukotriene
formation by Kupffer cell
s.
Liver
The liver is a vital organ present in vertebrates and some other animals. It has a wide range of functions, including detoxification, protein synthesis, and production of biochemicals necessary for digestion...
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An example of a hepatoprotective medicine is silibinin
Silibinin
Silibinin , also known as silybin, is the major active constituent of silymarin, standardized extract of the milk thistle seeds, containing mixture of flavonolignans consisting of among others of silibinin, isosilibinin, silicristin and silidianin. Silibinin itself is mixture of two diastereomers...
, derived from Milk Thistle
Milk thistle
The milk thistle is a thistle of the genus Silybum Adans., a flowering plant of the daisy family . They are native to the Mediterranean regions of Europe, North Africa and the Middle East...
, which selectively inhibits leukotriene
Leukotriene
Leukotrienes are fatty signaling molecules. They were first found in leukocytes . One of their roles is to trigger contractions in the smooth muscles lining the trachea; their overproduction is a major cause of inflammation in asthma and allergic rhinitis...
formation by Kupffer cell
Kupffer cell
Kupffer cells, also known as Browicz-Kupffer cells and stellate macrophages, are specialized macrophages located in the liver lining the walls of the sinusoids that form part of the reticuloendothelial system .-History:The cells were first observed by Karl Wilhelm von Kupffer in 1876...
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Herbs with potentially hepatoprotective constituents
- Almond oil
- Amomum xanthoides
- Arctium lappa
- Astragalus membranaceus
- Cichorium intybus
- Curcuma longa
- Cajanus indicus,
- Centella asiaticaCentella asiaticaCentella asiatica is a small herbaceous annual plant of the family Mackinlayaceae or subfamily Mackinlayoideae of family Apiaceae, and is native to India, Sri Lanka, northern Australia, Indonesia, Iran, Malaysia, Melanesia, Papua New Guinea, and other parts of Asia...
- Coccinia indica'
- EcliptaEcliptaEclipta is a genus of flowering plants in the daisy family....
- Flickingeria fimbriata
- Ganoderma lucidum
- Glycyrrhiza glabra
- Halenia elliptica (a medicinal herb of Tibetan folk medicine used to treat hepatitis.)
- Kalopanax pictus ?
- Murraya koenigiiCurry TreeThe curry tree is a tropical to sub-tropical tree in the family Rutaceae, which is native to India...
- Nymphaea stellata
- Ocimum sanctum
- Paeonia lactifloraPaeonia lactifloraPaeonia lactiflora, also Chinese Peony , and common garden peony is a herbaceous perennial flowering plant in the family Paeoniaceae, native to central and eastern Asia from eastern Tibet across northern China to eastern Siberia...
- Pergularia daemia
- Picrorhiza kurrooa
- Phyllanthus amarus
- Plumbago zeylanicaPlumbago zeylanicaPlumbago zeylanica, commonly known as Ceylon Leadwort or Doctorbush, is a species of plumbago with a pantropical distribution. Carl Linnaeus described the paleotropical P. zeylanica and neotropical P. scandens as separate species, but they are currently considered synonymous...
- Silybum marianum
- Scoparia dulcis
- Salvia miltiorrhizaSalvia miltiorrhizaSalvia miltiorrhiza , also known as red sage, Chinese sage, tan shen, or danshen, is a perennial plant in the genus Salvia, highly valued for its roots in traditional Chinese medicine. Native to China and Japan, it grows at elevation, preferring grassy places in forests, hillsides, and along...
- Scutellaria baicalensisScutellaria baicalensisScutellaria baicalensis is a species of flowering plant in the Lamiaceae family.-Medicinal uses:...
- Schisandra chinensisSchisandra chinensisSchisandra chinensis is a deciduous woody vine native to forests of Northern China and the Russian Far East. It is hardy in USDA Zone 4. The plant likes some shade with moist, well-drained soil...
- Terminalia catappaTerminalia catappaTerminalia catappa is a large tropical tree in the Leadwood tree family, Combretaceae. The tree has been spread widely by humans and the native range is uncertain. It has long been naturalised in a broad belt extending from Africa to Northern Australia and New Guinea through Southeast Asia and...
- Tinospora cordifoliaTinospora cordifoliaTinospora cordifolia, which is known by the common name Guduchi, is an herbaceous vine of the family Menispermaceae indigenous to the tropical areas of India, Myanmar and Sri Lanka....
- Zizyphus mauritiana
- Vitis thunbergii, V. flexuosaVitis flexuosaVitis flexuosa is a species of liana in the grape family. It has a very large native range in Asian tropical and temperate climate zones, including East Asia Vitis flexuosa is a species of liana in the grape family. It has a very large native range in Asian tropical and temperate climate zones,...
, and V. kelungensis - three common wild grapes from Taiwan - Paeonia lactiflora and Astragalus membranaceus:- The extract from the roots of P. lactiflora and A. membranaceus demonstrated better hepatoprotective activity than the herbs used individually.
- Chinese traditional prescriptions:-. Simo Yin , Guizhi Fuling Wan, Xieqing Wan, and Sini San.
- Ayurvedic herbs (30)