The Holtemme is a 47 km long tributary

Tributary

A tributary or affluent is a stream or river that flows into a main stem river or a lake. A tributary does not flow directly into a sea or ocean...

 of the river Bode

Bode

Bode may refer to:in people by surname:*Boyd Henry Bode , American academic and philosopher*Bruce Bode, MD, FACE, American diabetes specialist*Denise Bode , American politician*Erin Bode, American singer...

 in Saxony-Anhalt

Saxony-Anhalt

Saxony-Anhalt is a landlocked state of Germany. Its capital is Magdeburg and it is surrounded by the German states of Lower Saxony, Brandenburg, Saxony, and Thuringia.Saxony-Anhalt covers an area of...

, Germany

Germany

Germany , officially the Federal Republic of Germany , is a federal parliamentary republic in Europe. The country consists of 16 states while the capital and largest city is Berlin. Germany covers an area of 357,021 km2 and has a largely temperate seasonal climate...

.

It rises in the Harz mountains at the eastern foot of the Brocken, descends during its upper course as the Steinerne Renne

Steinerne Renne

The Steinerne Renne is a waterfall and natural monument near the town of Wernigerode in the Harz mountains of central Germany.- Location :The Steinerne Renne is located west of Hasserode in the borough of Wernigerode in a forested area at the foot of the Brocken...

, a steep stream bed riddled with granite rocks, flows through Hasserode

Hasserode

Hasserode has been a quarter in the town of Wernigerode since 1907, a town in the German state of Saxony-Anhalt.- Location :Hasserode lies at the foot of the Harz Mountains in the valley of the River Holtemme, whose upper reaches include the water cascade of the Steinerne Renne...

, Wernigerode

Wernigerode

Wernigerode is a town in the district of Harz, Saxony-Anhalt, Germany. Until 2007, it was the capital of the district of Wernigerode. Its population was 35,500 in 1999....

 and past their villages of Minsleben and Silstedt, through Derenburg

Derenburg

Derenburg is a town in the district of Harz, in Saxony-Anhalt, Germany. It is situated north of the Harz, approx. 9 km east of Wernigerode, and 10 km west of Halberstadt. Since 1 January 2010, it is part of the borough of Blankenburg am Harz....

 and Halberstadt

Halberstadt

Halberstadt is a town in the German state of Saxony-Anhalt and the capital of the district of Harz. It is located on the German Half-Timbered House Road and the Magdeburg–Thale railway....

 and discharges into the Bode.

In Wernigerode, not far from the western gate, the Zillierbach

Zillierbach

The Zillierbach is a stream in the Harz mountains of central Germany The Zillierbach (until 1558 called the Zilgerbach) is a stream in the Harz mountains of central Germany The Zillierbach (until 1558 called the Zilgerbach) is a stream in the Harz mountains of central Germany (Harz district in the...

, which is also known as the Flutrenne, merges into the Holtemme.