Hsp20
Encyclopedia
Heat shock protein Hsp20 is a family
of heat shock proteins.
Prokaryotic and eukaryotic organisms respond to heat shock
or other environmental stress by inducing the synthesis of proteins collectively known as heat-shock proteins (hsp). Amongst them is a family of proteins with an average molecular weight of 20 Kd, known as the hsp20 proteins. These seem to act as protein chaperones that can protect other proteins against heat-induced denaturation and aggregation. Hsp20 proteins seem to form large heterooligomeric aggregates. Structurally, this family is characterised by the presence of a conserved C-terminal domain of about 100 residues.
; CRYAB
; HSPB1; HSPB2
; HSPB3; HSPB6
; HSPB7; HSPB8
;
HSPB9;
Protein family
A protein family is a group of evolutionarily-related proteins, and is often nearly synonymous with gene family. The term protein family should not be confused with family as it is used in taxonomy....
of heat shock proteins.
Prokaryotic and eukaryotic organisms respond to heat shock
Heat shock
In biochemistry, heat shock is the effect of subjecting a cell to a higher temperature than that of the ideal body temperature of the organism from which the cell line was derived.-Heat shock response:...
or other environmental stress by inducing the synthesis of proteins collectively known as heat-shock proteins (hsp). Amongst them is a family of proteins with an average molecular weight of 20 Kd, known as the hsp20 proteins. These seem to act as protein chaperones that can protect other proteins against heat-induced denaturation and aggregation. Hsp20 proteins seem to form large heterooligomeric aggregates. Structurally, this family is characterised by the presence of a conserved C-terminal domain of about 100 residues.
Human proteins containing this domain
CRYAACRYAA
Alpha-crystallin A chain is a protein that in humans is encoded by the CRYAA gene.-Interactions:CRYAA has been shown to interact with CRYBB2, Hsp27, CRYGC and CRYAB.-Further reading:...
; CRYAB
CRYAB
Alpha-crystallin B chain is a protein that in humans is encoded by the CRYAB gene.-Interactions:CRYAB has been shown to interact with CRYBB2, Hsp27, HSPB2, CRYGC, PSMA3 and CRYAA.-External links:* -Further reading:...
; HSPB1; HSPB2
HSPB2
Heat shock protein beta-2 is a protein that in humans is encoded by the HSPB2 gene.-Interactions:HSPB2 has been shown to interact with TRAF6, HSPB8, Myotonic dystrophy protein kinase and CRYAB.-Further reading:...
; HSPB3; HSPB6
HSPB6
Heat shock protein beta-6 is a protein that in humans is encoded by the HSPB6 gene.HSPB6 also known as hsp20 is a 17-kDa member of the small heat shock family of proteins...
; HSPB7; HSPB8
HSPB8
Heat shock protein beta-8 is a protein that in humans is encoded by the HSPB8 gene.-Interactions:HSPB8 has been shown to interact with Hsp27 and HSPB2.-External links:*...
;
HSPB9;