Hyalobarrier
Encyclopedia
Hyalobarrier is a substance to keep tissue apart post surgery and therefore prevent adhesions. It contains autocross-linked hyaluronan
. Highly viscous due to condensation. Hyaluronan is present in cartilage and skin hence there is a natural metabolic pathway
for it. This gel is used to separate organs and tissue after surgery.
Scientific documentation so far covers the gynaecology speciality. IE Laparoscopic surgery
, hysteroscopy
/hysteroscopic surgery but also open surgery.
According to data in a Cochrane collaboration
review active action to prevent adhesions needs to be taken to a larger extent. The Cochrane report also states that the incidence of postsurgical adhesions is as high as 60 to 90%.
In a recent review by C Sutton (University of Surrey, Guilford UK), it is stated that Hyalobarrier is the only anti adhesive substance that has published data for intrauterine use.
Hyaluronan
Hyaluronan is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues...
. Highly viscous due to condensation. Hyaluronan is present in cartilage and skin hence there is a natural metabolic pathway
Metabolic pathway
In biochemistry, metabolic pathways are series of chemical reactions occurring within a cell. In each pathway, a principal chemical is modified by a series of chemical reactions. Enzymes catalyze these reactions, and often require dietary minerals, vitamins, and other cofactors in order to function...
for it. This gel is used to separate organs and tissue after surgery.
Scientific documentation so far covers the gynaecology speciality. IE Laparoscopic surgery
Laparoscopic surgery
Laparoscopic surgery, also called minimally invasive surgery , bandaid surgery, or keyhole surgery, is a modern surgical technique in which operations in the abdomen are performed through small incisions as opposed to the larger incisions needed in laparotomy.Keyhole surgery makes use of images...
, hysteroscopy
Hysteroscopy
Hysteroscopy is the inspection of the uterine cavity by endoscopy with access through the cervix. It allows for the diagnosis of intrauterine pathology and serves as a method for surgical intervention .-Method:...
/hysteroscopic surgery but also open surgery.
According to data in a Cochrane collaboration
Cochrane Collaboration
The Cochrane Collaboration is a group of over 28,000 volunteers in more than 100 countries who review the effects of health care interventions tested in biomedical randomized controlled trials. A few more recent reviews have also studied the results of non-randomized, observational studies...
review active action to prevent adhesions needs to be taken to a larger extent. The Cochrane report also states that the incidence of postsurgical adhesions is as high as 60 to 90%.
In a recent review by C Sutton (University of Surrey, Guilford UK), it is stated that Hyalobarrier is the only anti adhesive substance that has published data for intrauterine use.
Additional information
- Adhesions
- HysteroscopyHysteroscopyHysteroscopy is the inspection of the uterine cavity by endoscopy with access through the cervix. It allows for the diagnosis of intrauterine pathology and serves as a method for surgical intervention .-Method:...
- LaparoscopyLaparoscopyLaparoscopy is an operation performed in the abdomen or pelvis through small incisions with the aid of a camera...
- Asherman's syndromeAsherman's syndromeAsherman's syndrome , also called "uterine synechiae" or intrauterine adhesions , presents a condition characterized by the presence of adhesions and/or fibrosis within the uterine cavity due to scars...