Hydroxycorticosteroids
Encyclopedia
Hydroxycorticosteroids are corticosteroids that have an additional hydroxy
(-OH) group.
There are two main positions where the hydroxy are added: at the 11, and at the 17.
11-hydroxycorticosteroids include:
17-hydroxycorticosteroids include:
Hydroxyl
A hydroxyl is a chemical group containing an oxygen atom covalently bonded with a hydrogen atom. In inorganic chemistry, the hydroxyl group is known as the hydroxide ion, and scientists and reference works generally use these different terms though they refer to the same chemical structure in...
(-OH) group.
There are two main positions where the hydroxy are added: at the 11, and at the 17.
At the 11 position
- aldosteroneAldosteroneAldosterone is a hormone that increases the reabsorption of sodium ions and water and the release of potassium in the collecting ducts and distal convoluted tubule of the kidneys' functional unit, the nephron. This increases blood volume and, therefore, increases blood pressure. Drugs that...
- corticosteroneCorticosteroneCorticosterone is a 21-carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands.-Roles:In many species, including amphibians, reptiles, rodents and birds, corticosterone is a main glucocorticoid, involved in regulation of fuel, immune reactions, and stress...
- hydrocortisone
At the 17 position
- cortisoneCortisoneCortisone is a steroid hormone. It is one of the main hormones released by the adrenal gland in response to stress. In chemical structure, it is a corticosteroid closely related to corticosterone. It is used to treat a variety of ailments and can be administered intravenously, orally,...
- hydrocortisone