Interstate 81
Overview
 
Interstate 81 is an Interstate Highway in the eastern part of the United States
United States
The United States of America is a federal constitutional republic comprising fifty states and a federal district...

. Its southern terminus is at Interstate 40
Interstate 40
Interstate 40 is the third-longest major east–west Interstate Highway in the United States, after I-90 and I-80. Its western end is at Interstate 15 in Barstow, California; its eastern end is at a concurrency of U.S. Route 117 and North Carolina Highway 132 in Wilmington, North Carolina...

 in Dandridge, Tennessee
Dandridge, Tennessee
Dandridge is a town in Jefferson County, Tennessee, United States. It is the county seat of Jefferson County. It is part of the Morristown, Tennessee Metropolitan Statistical Area....

; its northern terminus is on Wellesley Island
Wellesley Island
Wellesley Island in Jefferson County, New York, USA is partially in the Town of Orleans and partially in the Town of Alexandria.-Geography:...

 (near Fishers Landing, New York
Fishers Landing, New York
Fishers Landing is a hamlet in the town of Orleans in Jefferson County, New York just southwest of Grass Point State Park. This is a favorite vacation destination for many coming to the Thousand Islands. Foxy's Restaurant is a well known location on the St. Lawrence River...

) at the Canadian border, where the Thousand Islands Bridge
Thousand Islands Bridge
The Thousand Islands Bridge is an international bridge system over the Saint Lawrence River connecting northern New York in the United States with southeastern Ontario in Canada. Constructed in 1937, with additions in 1959, the bridges span the United States-Canada border in the middle of the...

 connects it to Highway 401, the main freeway connecting Detroit to Toronto
Toronto
Toronto is the provincial capital of Ontario and the largest city in Canada. It is located in Southern Ontario on the northwestern shore of Lake Ontario. A relatively modern city, Toronto's history dates back to the late-18th century, when its land was first purchased by the British monarchy from...

 and Toronto
Toronto
Toronto is the provincial capital of Ontario and the largest city in Canada. It is located in Southern Ontario on the northwestern shore of Lake Ontario. A relatively modern city, Toronto's history dates back to the late-18th century, when its land was first purchased by the British monarchy from...

 to Montreal
Montreal
Montreal is a city in Canada. It is the largest city in the province of Quebec, the second-largest city in Canada and the seventh largest in North America...

.

Interstate 81 largely traces the path of the Appalachian Mountains
Appalachian Mountains
The Appalachian Mountains #Whether the stressed vowel is or ,#Whether the "ch" is pronounced as a fricative or an affricate , and#Whether the final vowel is the monophthong or the diphthong .), often called the Appalachians, are a system of mountains in eastern North America. The Appalachians...

, often paralleling its older U.S. highway
United States Numbered Highways
The system of United States Numbered Highways is an integrated system of roads and highways in the United States numbered within a nationwide grid...

 counterpart, U.S. Route 11
U.S. Route 11
U.S. Route 11 is a north–south United States highway extending 1,645 miles across the eastern United States. The southern terminus of the route is at U.S. Route 90 in the Bayou Sauvage National Wildlife Refuge in eastern New Orleans, Louisiana. The northern terminus is at the United...

.
 
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