Ioan C. Cantacuzino was a renowned Romania

Romania

Romania is a country located at the crossroads of Central and Southeastern Europe, on the Lower Danube, within and outside the Carpathian arch, bordering on the Black Sea...

n physician

Physician

A physician is a health care provider who practices the profession of medicine, which is concerned with promoting, maintaining or restoring human health through the study, diagnosis, and treatment of disease, injury and other physical and mental impairments...

 and bacteriologist, a professor at the Romanian School of Medicine and Pharmacy

Carol Davila University of Medicine and Pharmacy

Carol Davila University of Medicine and Pharmacy is a state-run health sciences University in Bucharest, Romania. It is the largest institution of its kind in Romania with over 2.865 employees, 1.654 teachers and over 4.800 students...

 and a member of the Romanian Academy

Romanian Academy

The Romanian Academy is a cultural forum founded in Bucharest, Romania, in 1866. It covers the scientific, artistic and literary domains. The academy has 181 acting members who are elected for life....

. He was the founder of the fields of microbiology

Microbiology

Microbiology is the study of microorganisms, which are defined as any microscopic organism that comprises either a single cell , cell clusters or no cell at all . This includes eukaryotes, such as fungi and protists, and prokaryotes...

 and experimental medicine in Romania, and creator of the Ioan Cantacuzino Institute.

Biography

Born in Bucharest

Bucharest

Bucharest is the capital municipality, cultural, industrial, and financial centre of Romania. It is the largest city in Romania, located in the southeast of the country, at , and lies on the banks of the Dâmbovița River....

 as a member of the Cantacuzino family

Cantacuzino family

The Cantacuzino or Cantacuzène family is an old boyar family of Wallachia and Moldavia, a branch of Greek Kantakouzinos family, allegedly descended from the Byzantine Emperor John VI Cantacuzenus. No definite genealogical links between Byzantine Greek and Romanian Cantacuzinos have been established...

, he graduated from the University of Paris

University of Paris

The University of Paris was a university located in Paris, France and one of the earliest to be established in Europe. It was founded in the mid 12th century, and officially recognized as a university probably between 1160 and 1250...

' Faculty of Sciences and Faculty of Medicine, and worked at several hospitals in Paris

Paris

Paris is the capital and largest city in France, situated on the river Seine, in northern France, at the heart of the Île-de-France region...

, obtaining his doctorate

Doctorate

A doctorate is an academic degree or professional degree that in most countries refers to a class of degrees which qualify the holder to teach in a specific field, A doctorate is an academic degree or professional degree that in most countries refers to a class of degrees which qualify the holder...

 in 1894. Later in the same year, he began his academic career as a deputy professor at the University of Iaşi, and returned to Paris after two years to serve on the staff of the Pasteur Institute

Pasteur Institute

The Pasteur Institute is a French non-profit private foundation dedicated to the study of biology, micro-organisms, diseases, and vaccines. It is named after Louis Pasteur, who made some of the greatest breakthroughs in modern medicine at the time, including pasteurization and vaccines for anthrax...

, where he worked under the direction of Ilya Ilyich Mechnikov

Ilya Ilyich Mechnikov

Ilya Ilyich Mechnikov was a Russian biologist, zoologist and protozoologist, best remembered for his pioneering research into the immune system. Mechnikov received the Nobel Prize in Medicine in 1908, shared with Paul Ehrlich, for his work on phagocytosis...

.

In 1901, Cantacuzino was assigned a teaching position in Bucharest, where he became a major influence on a generation of scientists. His discoveries were relevant in the treatment of cholera

Cholera

Cholera is an infection of the small intestine that is caused by the bacterium Vibrio cholerae. The main symptoms are profuse watery diarrhea and vomiting. Transmission occurs primarily by drinking or eating water or food that has been contaminated by the diarrhea of an infected person or the feces...

, epidemic typhus, tuberculosis

Tuberculosis

Tuberculosis, MTB, or TB is a common, and in many cases lethal, infectious disease caused by various strains of mycobacteria, usually Mycobacterium tuberculosis. Tuberculosis usually attacks the lungs but can also affect other parts of the body...

, and scarlet fever

Scarlet fever

Scarlet fever is a disease caused by exotoxin released by Streptococcus pyogenes. Once a major cause of death, it is now effectively treated with antibiotics...

. As a disciple of Mechnikov, he devoted part of his research to expanding on the latter's field of interest (phagocyte

Phagocyte

Phagocytes are the white blood cells that protect the body by ingesting harmful foreign particles, bacteria, and dead or dying cells. Their name comes from the Greek phagein, "to eat" or "devour", and "-cyte", the suffix in biology denoting "cell", from the Greek kutos, "hollow vessel". They are...

s, the body's means of defence

Immune system

An immune system is a system of biological structures and processes within an organism that protects against disease by identifying and killing pathogens and tumor cells. It detects a wide variety of agents, from viruses to parasitic worms, and needs to distinguish them from the organism's own...

 against pathogen

Pathogen

A pathogen gignomai "I give birth to") or infectious agent — colloquially, a germ — is a microbe or microorganism such as a virus, bacterium, prion, or fungus that causes disease in its animal or plant host...

s, as well as the issue of immunity and invertebrate

Invertebrate

An invertebrate is an animal without a backbone. The group includes 97% of all animal species – all animals except those in the chordate subphylum Vertebrata .Invertebrates form a paraphyletic group...

s). He invented the notion of contact immunity

Contact immunity

Contact immunity is the property of some vaccines, where a vaccinated individual can confer immunity upon unimmunized individuals through contact with bodily fluids or excrement...

.

During the Second Balkan War

Second Balkan War

The Second Balkan War was a conflict which broke out when Bulgaria, dissatisfied with its share of the spoils of the First Balkan War, attacked its former allies, Serbia and Greece, on 29 June 1913. Bulgaria had a prewar agreement about the division of region of Macedonia...

, Cantacuzino was appointed head of the staff combatting the cholera epidemic

Epidemic

In epidemiology, an epidemic , occurs when new cases of a certain disease, in a given human population, and during a given period, substantially exceed what is expected based on recent experience...

 in the ranks of the Romanian Army stationed in Dobruja

Dobruja

Dobruja is a historical region shared by Bulgaria and Romania, located between the lower Danube river and the Black Sea, including the Danube Delta, Romanian coast and the northernmost part of the Bulgarian coast...

; he was assigned to the same position during the Romanian campaign

Romanian Campaign (World War I)

The Romanian Campaign was part of the Balkan theatre of World War I, with Romania and Russia allied against the armies of the Central Powers. Fighting took place from August 1916 to December 1917, across most of present-day Romania, including Transylvania, which was part of the Austro-Hungarian...

 in World War I

World War I

World War I , which was predominantly called the World War or the Great War from its occurrence until 1939, and the First World War or World War I thereafter, was a major war centred in Europe that began on 28 July 1914 and lasted until 11 November 1918...

, in the fight against typhus. He founded and led the scientific magazines Revista Ştiinţelor Medicale and Archives roumaines de pathologie expérimentale, and regularly contributed to the literary magazine

Literary magazine

A literary magazine is a periodical devoted to literature in a broad sense. Literary magazines usually publish short stories, poetry and essays along with literary criticism, book reviews, biographical profiles of authors, interviews and letters...

 Viaţa Românească

Viata Româneasca

Viaţa Românească, originally Viaţa Romînească , is a monthly literary magazine published in Romania...

(replacing Paul Bujor on the editorial board). A collaborator of Constantin Stere

Constantin Stere

Constantin G. Stere or Constantin Sterea was a Romanian writer, jurist, politician, ideologue of the Poporanist trend, and, in March 1906, co-founder Constantin G. Stere or Constantin Sterea (Romanian; , Konstantin Yegorovich Stere or Константин Георгиевич Стере, Konstantin Georgiyevich Stere;...

, he was noted as a Poporanist

Poporanism

The word “poporanism” is derived from “popor”, meaning “people” in the Romanian language. The ideology of Romanian Populism and poporanism are interchangeable. Founded by Constantin Stere in the early 1890s, populism is distinguished by its opposition to socialism, promotion of voting rights for...

 disciple of Constantin Dobrogeanu-Gherea

Constantin Dobrogeanu-Gherea

Constantin Dobrogeanu-Gherea was a Romanian Marxist theorist, politician, sociologist, literary critic, and journalist....

.