John Franklin Enders
Encyclopedia
John Franklin Enders was an American medical scientist and Nobel laureate. Enders had been called "The Father of Modern Vaccines."

Life

Enders was born in West Hartford, Connecticut
West Hartford, Connecticut
West Hartford is a town located in Hartford County, Connecticut, United States. The town was incorporated in 1854. Prior to that date, the town was a parish of Hartford....

 and was educated at the Noah Webster
Noah Webster
Noah Webster was an American educator, lexicographer, textbook pioneer, English spelling reformer, political writer, editor, and prolific author...

 School at Hartford and St. Paul's School
St. Paul's School (Concord, New Hampshire)
St. Paul's School is a highly selective college-preparatory, coeducational boarding school in Concord, New Hampshire affiliated with the Episcopal Church. The school is one of only six remaining 100% residential boarding schools in the U.S. The New Hampshire campus currently serves 533 students,...

 in Concord, New Hampshire
Concord, New Hampshire
The city of Concord is the capital of the state of New Hampshire in the United States. It is also the county seat of Merrimack County. As of the 2010 census, its population was 42,695....

. He then attended Yale University
Yale University
Yale University is a private, Ivy League university located in New Haven, Connecticut, United States. Founded in 1701 in the Colony of Connecticut, the university is the third-oldest institution of higher education in the United States...

 for a short time before entering the United States Army Air Corps
United States Army Air Corps
The United States Army Air Corps was a forerunner of the United States Air Force. Renamed from the Air Service on 2 July 1926, it was part of the United States Army and the predecessor of the United States Army Air Forces , established in 1941...

 in 1918.

After returning from war he graduated from Yale, where he was a member of Scroll and Key
Scroll and Key
The Scroll and Key Society is a secret society, founded in 1842 at Yale University, in New Haven, Connecticut. It is the wealthiest and second oldest Yale secret society...

 as well as Delta Kappa Epsilon
Delta Kappa Epsilon
Delta Kappa Epsilon is a fraternity founded at Yale College in 1844 by 15 men of the sophomore class who had not been invited to join the two existing societies...

, and went on to become a businessman in real estate in 1922. He tried his hand at several careers before choosing to work in the biological field studying infectious diseases, gaining a Ph.D.
Ph.D.
A Ph.D. is a Doctor of Philosophy, an academic degree.Ph.D. may also refer to:* Ph.D. , a 1980s British group*Piled Higher and Deeper, a web comic strip*PhD: Phantasy Degree, a Korean comic series* PhD Docbook renderer, an XML renderer...

 at Harvard in 1930.

In 1954, while working at Children's Hospital Boston
Children's Hospital Boston
Children's Hospital Boston is a 396-licensed bed children's hospital in the Longwood Medical and Academic Area of Boston, Massachusetts.At 300 Longwood Avenue, Children's is adjacent both to its teaching affiliate, Harvard Medical School, and to Dana-Farber Cancer Institute...

, Enders, Thomas Huckle Weller
Thomas Huckle Weller
Thomas Huckle Weller was an American virologist. He, John Franklin Enders and Frederick Chapman Robbins were awarded a Nobel Prize in Physiology or Medicine in 1954 for showing how to cultivate poliomyelitis viruses in a test tube, using tissue from a monkey.Weller was born and grew up in Ann...

, and Frederick Chapman Robbins were awarded the Nobel Prize in Physiology or Medicine
Nobel Prize in Physiology or Medicine
The Nobel Prize in Physiology or Medicine administered by the Nobel Foundation, is awarded once a year for outstanding discoveries in the field of life science and medicine. It is one of five Nobel Prizes established in 1895 by Swedish chemist Alfred Nobel, the inventor of dynamite, in his will...

 "for their discovery of the ability of poliomyelitis
Poliomyelitis
Poliomyelitis, often called polio or infantile paralysis, is an acute viral infectious disease spread from person to person, primarily via the fecal-oral route...

 viruses to grow in cultures of various types of tissue". This work was the first to show that viruses of this type could be grown and manipulated outside of the body. It was this technique dubbed the Enders-Weller-Robbins method that Jonas Salk
Jonas Salk
Jonas Edward Salk was an American medical researcher and virologist, best known for his discovery and development of the first safe and effective polio vaccine. He was born in New York City to parents from Ashkenazi Jewish Russian immigrant families...

 used to develop the polio vaccine
Polio vaccine
Two polio vaccines are used throughout the world to combat poliomyelitis . The first was developed by Jonas Salk and first tested in 1952. Announced to the world by Salk on April 12, 1955, it consists of an injected dose of inactivated poliovirus. An oral vaccine was developed by Albert Sabin...

 in 1952. After a large-scale test of the vaccine proved successful in 1954, Salk appeared on a radio show and announced his success to the world. Although he never claimed the credit for himself, he also did not offer up any credit to any of his colleagues, including Enders, Weller, and Robbins, whose technique made his success possible. Salk became a hero to the public, but was somewhat shunned by the scientific community. Despite this misappropriated credit many professionals in the field still regard Enders', Weller's and Robbins' work as substantial have given Enders the title of "The Father of Modern Vaccines".

On October 4, 1960, the New York Times reported that Dr Enders was leading a team testing a measles
Measles
Measles, also known as rubeola or morbilli, is an infection of the respiratory system caused by a virus, specifically a paramyxovirus of the genus Morbillivirus. Morbilliviruses, like other paramyxoviruses, are enveloped, single-stranded, negative-sense RNA viruses...

 vaccine on 1,500 retarded children in New York City and another 4,000 children in Nigeria
Nigeria
Nigeria , officially the Federal Republic of Nigeria, is a federal constitutional republic comprising 36 states and its Federal Capital Territory, Abuja. The country is located in West Africa and shares land borders with the Republic of Benin in the west, Chad and Cameroon in the east, and Niger in...

. By late 1961, the vaccine was proven to be completely effective.

Enders died in 1985 in Waterford, Connecticut
Waterford, Connecticut
Waterford is a town in New London County, Connecticut, United States. It is named after Waterford, Ireland. The population was 19,152 at the 2000 census. The town center is listed as a census-designated place .-Geography:...

, aged 88.

Honors

  • 1946: Fellow of the American Academy of Arts and Sciences
    American Academy of Arts and Sciences
    The American Academy of Arts and Sciences is an independent policy research center that conducts multidisciplinary studies of complex and emerging problems. The Academy’s elected members are leaders in the academic disciplines, the arts, business, and public affairs.James Bowdoin, John Adams, and...

  • 1953: Election to National Academy of Sciences
    United States National Academy of Sciences
    The National Academy of Sciences is a corporation in the United States whose members serve pro bono as "advisers to the nation on science, engineering, and medicine." As a national academy, new members of the organization are elected annually by current members, based on their distinguished and...

  • 1953: Passano Award
  • 1954: Albert Lasker Award for Basic Medical Research
    Albert Lasker Award for Basic Medical Research
    The Albert Lasker Award for Basic Medical Research is one of the prizes awarded by the Lasker Foundation for the understanding, diagnosis, prevention, treatment, and cure of disease...

  • 1954:Nobel Prize in Physiology or Medicine
    Nobel Prize in Physiology or Medicine
    The Nobel Prize in Physiology or Medicine administered by the Nobel Foundation, is awarded once a year for outstanding discoveries in the field of life science and medicine. It is one of five Nobel Prizes established in 1895 by Swedish chemist Alfred Nobel, the inventor of dynamite, in his will...

  • 1955: Charles V. Chapin
    Charles V. Chapin
    Charles Value Chapin was a pioneer in public- health practice, serving as one of the Health Officers for Providence, Rhode Island between 1884 and 1932...

     Medal
  • 1955: Gordon Wilson
    Gordon Wilson
    Gordon Wilson may refer to:*Gordon Wilson , former leader of the Scottish National Party*Gordon Wilson , leader of the British Columbia Liberal Party...

     Medal
  • 1958: Election to the Polio Hall of Fame
    Polio Hall of Fame
    The Polio Hall of Fame consists of a linear grouping of sculptured busts of fifteen scientists and two laymen who made important contributions to the knowledge and treatment of poliomyelitis...

     at Warm Springs, Georgia
    Warm Springs, Georgia
    Warm Springs is a city in Meriwether County, Georgia, United States. The population was 478 at the 2010 census.-History:Warm Springs first came to prominence in the 19th century as a spa town, due to its mineral springs which flow constantly at nearly 32 °C...

  • 1961: TIME
    Time
    Time is a part of the measuring system used to sequence events, to compare the durations of events and the intervals between them, and to quantify rates of change such as the motions of objects....

     Man of the Year
    Man of the Year
    A Man of the Year award usually refers to a person nominated as the most influential or meritous in a business, organisation, a specific form of human endeavour, or amongst humanity at large...

  • 1962: Robert Koch
    Robert Koch
    Heinrich Hermann Robert Koch was a German physician. He became famous for isolating Bacillus anthracis , the Tuberculosis bacillus and the Vibrio cholerae and for his development of Koch's postulates....

     Medaille, Germany
  • 1963: Presidential Medal of Freedom
    Presidential Medal of Freedom
    The Presidential Medal of Freedom is an award bestowed by the President of the United States and is—along with thecomparable Congressional Gold Medal bestowed by an act of U.S. Congress—the highest civilian award in the United States...

    , United States
  • 1967: Foreign Member, Royal Society of London
  • 1981: Galen Medal of the Worshipful Society of Apothecaries, London.


Honorary doctoral degrees from thirteen universities.

Further reading

  • Thomas H. Weller and Frederick C. Robb: John Franklin Enders (1897–1985), A Biographical Memoir, Washington (D.C.), 1991 (NAS
    Nas
    Nasir bin Olu Dara Jones, who performs under the name Nas , formerly Nasty Nas, is an American rapper and actor. He is regarded as one of the most important figures in hip hop and one of the most skilled and influential rappers of all-time...

     publication also online PDF)

External links

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