John Grange
Encyclopedia
Professor John Grange is an English; immunologist, epidemiologist, researcher
Researcher
A researcher is somebody who performs research, the search for knowledge or in general any systematic investigation to establish facts. Researchers can work in academic, industrial, government, or private institutions.-Examples of research institutions:...

, and academic, and is one of Europe's leading tuberculosis
Tuberculosis
Tuberculosis, MTB, or TB is a common, and in many cases lethal, infectious disease caused by various strains of mycobacteria, usually Mycobacterium tuberculosis. Tuberculosis usually attacks the lungs but can also affect other parts of the body...

 specialists.

Education

Grange was educated at Gresham's School
Gresham's School
Gresham’s School is an independent coeducational boarding school in Holt in North Norfolk, England, a member of the HMC.The school was founded in 1555 by Sir John Gresham as a free grammar school for forty boys, following King Henry VIII's dissolution of the Augustinian priory at Beeston Regis...

, Holt, Norfolk
Holt, Norfolk
Holt is a market town and civil parish in the English county of Norfolk. The town is north of the city of Norwich, west of Cromer and east of King's Lynn. The town is on the route of the A148 King's Lynn to Cromer road. The nearest railway station is in the town of Sheringham where access to the...

, and then from 1962 to 1967 at the Middlesex Hospital Medical School of the University of London
University of London
-20th century:Shortly after 6 Burlington Gardens was vacated, the University went through a period of rapid expansion. Bedford College, Royal Holloway and the London School of Economics all joined in 1900, Regent's Park College, which had affiliated in 1841 became an official divinity school of the...

.

Career

After qualification as a physician, Grange joined the Research Department at the Middlesex Hospital, where he studied the genus Mycobacterium and the diseases it causes in humans and other animals. This followed a stay in Zaire
Zaire
The Republic of Zaire was the name of the present Democratic Republic of the Congo between 27 October 1971 and 17 May 1997. The name of Zaire derives from the , itself an adaptation of the Kongo word nzere or nzadi, or "the river that swallows all rivers".-Self-proclaimed Father of the Nation:In...

 to study the Buruli ulcer
Buruli ulcer
The Buruli ulcer is an infectious disease caused by Mycobacterium ulcerans. The genus also includes the causative agents of tuberculosis and leprosy...

. His doctoral thesis
Thesis
A dissertation or thesis is a document submitted in support of candidature for an academic degree or professional qualification presenting the author's research and findings...

 was on the classification of certain rapidly growing mycobacteria and led to research on the development of bacteriophage
Bacteriophage
A bacteriophage is any one of a number of viruses that infect bacteria. They do this by injecting genetic material, which they carry enclosed in an outer protein capsid...

 typing of mycobacteria for epidemiology
Epidemiology
Epidemiology is the study of health-event, health-characteristic, or health-determinant patterns in a population. It is the cornerstone method of public health research, and helps inform policy decisions and evidence-based medicine by identifying risk factors for disease and targets for preventive...

.

Next he was appointed Reader in Microbiology
Microbiology
Microbiology is the study of microorganisms, which are defined as any microscopic organism that comprises either a single cell , cell clusters or no cell at all . This includes eukaryotes, such as fungi and protists, and prokaryotes...

 at the National Heart and Lung Institute, where his interests turned to the immunology
Immunology
Immunology is a broad branch of biomedical science that covers the study of all aspects of the immune system in all organisms. It deals with the physiological functioning of the immune system in states of both health and diseases; malfunctions of the immune system in immunological disorders ; the...

 and epidemiology
Epidemiology
Epidemiology is the study of health-event, health-characteristic, or health-determinant patterns in a population. It is the cornerstone method of public health research, and helps inform policy decisions and evidence-based medicine by identifying risk factors for disease and targets for preventive...

 of tuberculosis
Tuberculosis
Tuberculosis, MTB, or TB is a common, and in many cases lethal, infectious disease caused by various strains of mycobacteria, usually Mycobacterium tuberculosis. Tuberculosis usually attacks the lungs but can also affect other parts of the body...

. From there he became assistant lecturer (1969-1970) at the Bland Sutton Institute of Pathology of Middlesex Hospital Medical School, University of London
University of London
-20th century:Shortly after 6 Burlington Gardens was vacated, the University went through a period of rapid expansion. Bedford College, Royal Holloway and the London School of Economics all joined in 1900, Regent's Park College, which had affiliated in 1841 became an official divinity school of the...

 and then lecturer in the same school's Department of Microbiology from 1971 to 1976.

From 1976 to 2000, Grange was Reader in Clinical Microbiology at the Imperial College School of Medicine
Imperial College School of Medicine
The Imperial College School of Medicine is the medical school of Imperial College London in England, and one of the United Hospitals....

 and honorary consultant Microbiologist to the Royal Brompton NHS Trust.

Between 1978 and 1995, he undertook a series of visits to Indonesia
Indonesia
Indonesia , officially the Republic of Indonesia , is a country in Southeast Asia and Oceania. Indonesia is an archipelago comprising approximately 13,000 islands. It has 33 provinces with over 238 million people, and is the world's fourth most populous country. Indonesia is a republic, with an...

 to pursue research into the immunology
Immunology
Immunology is a broad branch of biomedical science that covers the study of all aspects of the immune system in all organisms. It deals with the physiological functioning of the immune system in states of both health and diseases; malfunctions of the immune system in immunological disorders ; the...

 and epidemiology
Epidemiology
Epidemiology is the study of health-event, health-characteristic, or health-determinant patterns in a population. It is the cornerstone method of public health research, and helps inform policy decisions and evidence-based medicine by identifying risk factors for disease and targets for preventive...

 of tuberculosis
Tuberculosis
Tuberculosis, MTB, or TB is a common, and in many cases lethal, infectious disease caused by various strains of mycobacteria, usually Mycobacterium tuberculosis. Tuberculosis usually attacks the lungs but can also affect other parts of the body...

.

From 1985 to 1995, he was an honorary research fellow at King's College Hospital Medical School. After retirement from ICL he became a Visiting Professor at the University College London
University College London
University College London is a public research university located in London, United Kingdom and the oldest and largest constituent college of the federal University of London...

 Centre for Infectious Disease and International Health.

In recent years, Grange's interests have turned to the causes of the world tuberculosis
Tuberculosis
Tuberculosis, MTB, or TB is a common, and in many cases lethal, infectious disease caused by various strains of mycobacteria, usually Mycobacterium tuberculosis. Tuberculosis usually attacks the lungs but can also affect other parts of the body...

 pandemic
Pandemic
A pandemic is an epidemic of infectious disease that is spreading through human populations across a large region; for instance multiple continents, or even worldwide. A widespread endemic disease that is stable in terms of how many people are getting sick from it is not a pandemic...

 - poverty, inequity and injustice. He retired early from Imperial College London
Imperial College London
Imperial College London is a public research university located in London, United Kingdom, specialising in science, engineering, business and medicine...

 and to work for the British charity TB Alert
TB Alert
TB Alert is a charity working to raise awareness about and support effective treatment of the disease tuberculosis in the UK and internationally. It was registered in 1998 and launched on World Tuberculosis Day in 1999 in response to the resurgence of tuberculosis in the UK and worldwide...

, the Consultation on Health of the World Council of Churches
World Council of Churches
The World Council of Churches is a worldwide fellowship of 349 global, regional and sub-regional, national and local churches seeking unity, a common witness and Christian service. It is a Christian ecumenical organization that is based in the Ecumenical Centre in Geneva, Switzerland...

 and the International Society for Human Values.

Career Related Activities

  • Member of the International Union Against Tuberculosis and Lung Disease
  • Founder member of the European Society for Mycobacteriology
  • Founder, TB Alert
    TB Alert
    TB Alert is a charity working to raise awareness about and support effective treatment of the disease tuberculosis in the UK and internationally. It was registered in 1998 and launched on World Tuberculosis Day in 1999 in response to the resurgence of tuberculosis in the UK and worldwide...

    , 1998
  • Trustee, TB Alert
    TB Alert
    TB Alert is a charity working to raise awareness about and support effective treatment of the disease tuberculosis in the UK and internationally. It was registered in 1998 and launched on World Tuberculosis Day in 1999 in response to the resurgence of tuberculosis in the UK and worldwide...

    , 1998-2000
  • Member, Scientific Advisory Board of TB Alert
    TB Alert
    TB Alert is a charity working to raise awareness about and support effective treatment of the disease tuberculosis in the UK and internationally. It was registered in 1998 and launched on World Tuberculosis Day in 1999 in response to the resurgence of tuberculosis in the UK and worldwide...

    , 2001 to date
  • President, TB Focus since 2000
  • Editor of Tubercle, 1990-1992
  • Associate Editor of Tubercle and Lung Disease, 1992-1997
  • Associate Editor of International Journal of Tuberculosis and Lung Disease 1997-1999
  • Member of editorial board of Journal of Applied Bacteriology 1985-1990.

Degrees

1967 - Bachelor of Medicine (London)
1967 - Bachelor of Surgery (London)
1974 - Doctor of Medicine (London)
1981 - Master of Science, Immunology (London)

Sources

Professor John Grange at UCL
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