Keliximab
Encyclopedia
Keliximab is a monoclonal antibody for the treatment of severe chronic asthma
. It suppresses the immune reaction by binding to white blood cells via the protein CD4
. The drug is a chimeric antibody from Macaca irus and Homo sapiens.
Asthma
Asthma is the common chronic inflammatory disease of the airways characterized by variable and recurring symptoms, reversible airflow obstruction, and bronchospasm. Symptoms include wheezing, coughing, chest tightness, and shortness of breath...
. It suppresses the immune reaction by binding to white blood cells via the protein CD4
CD4
CD4 is a glycoprotein expressed on the surface of T helper cells, monocytes, macrophages, and dendritic cells. It was discovered in the late 1970s and was originally known as leu-3 and T4 before being named CD4 in 1984...
. The drug is a chimeric antibody from Macaca irus and Homo sapiens.