Laurence Hurst
Encyclopedia
Laurence D. Hurst is a Professor of Evolution
ary Genetics
in the Department of Biology
and Biochemistry
at The University of Bath
. Hurst completed his Bachelor of Arts
in Zoology
at Churchill College, Cambridge
in 1987. After a year at Harvard University
he returned to the UK, obtaining a D.Phil at the University of Oxford
in 1991 under the supervision of W. D. Hamilton
and Alan Grafen
. He was a Royal Society
Research Fellow at the University of Cambridge
from 1993 to 1996 and has been a Professor at the University of Bath since 1997.
His research interests include evolution, genetics and genomics using computational
and mathematical techniques to understand the way genes and genomes evolve. This has resulted in work on housekeeping gene
s, gene orders
and the evolution of drug resistance
in Staphylococcus aureus
, Saccharomyces cerevisiae
and the evolution of sexual reproduction / sexual dimorphism
.
Evolution
Evolution is any change across successive generations in the heritable characteristics of biological populations. Evolutionary processes give rise to diversity at every level of biological organisation, including species, individual organisms and molecules such as DNA and proteins.Life on Earth...
ary Genetics
Genetics
Genetics , a discipline of biology, is the science of genes, heredity, and variation in living organisms....
in the Department of Biology
Biology
Biology is a natural science concerned with the study of life and living organisms, including their structure, function, growth, origin, evolution, distribution, and taxonomy. Biology is a vast subject containing many subdivisions, topics, and disciplines...
and Biochemistry
Biochemistry
Biochemistry, sometimes called biological chemistry, is the study of chemical processes in living organisms, including, but not limited to, living matter. Biochemistry governs all living organisms and living processes...
at The University of Bath
University of Bath
The University of Bath is a campus university located in Bath, United Kingdom. It received its Royal Charter in 1966....
. Hurst completed his Bachelor of Arts
Bachelor of Arts
A Bachelor of Arts , from the Latin artium baccalaureus, is a bachelor's degree awarded for an undergraduate course or program in either the liberal arts, the sciences, or both...
in Zoology
Zoology
Zoology |zoölogy]]), is the branch of biology that relates to the animal kingdom, including the structure, embryology, evolution, classification, habits, and distribution of all animals, both living and extinct...
at Churchill College, Cambridge
Churchill College, Cambridge
Churchill College is a constituent college of the University of Cambridge, England.In 1958, a Trust was established with Sir Winston Churchill as its Chairman of Trustees, to build and endow a college for 60 fellows and 540 Students as a national and Commonwealth memorial to Winston Churchill; its...
in 1987. After a year at Harvard University
Harvard University
Harvard University is a private Ivy League university located in Cambridge, Massachusetts, United States, established in 1636 by the Massachusetts legislature. Harvard is the oldest institution of higher learning in the United States and the first corporation chartered in the country...
he returned to the UK, obtaining a D.Phil at the University of Oxford
University of Oxford
The University of Oxford is a university located in Oxford, United Kingdom. It is the second-oldest surviving university in the world and the oldest in the English-speaking world. Although its exact date of foundation is unclear, there is evidence of teaching as far back as 1096...
in 1991 under the supervision of W. D. Hamilton
W. D. Hamilton
William Donald Hamilton FRS was a British evolutionary biologist, widely recognised as one of the greatest evolutionary theorists of the 20th century....
and Alan Grafen
Alan Grafen
Alan Grafen is a Scottish ethologist and evolutionary biologist. He currently teaches and undertakes research at St John's College, Oxford. Along with regular contributions to scientific journals, Grafen is known publicly for his work as co-editor of the 2006 festschrift Richard Dawkins: How a...
. He was a Royal Society
Royal Society
The Royal Society of London for Improving Natural Knowledge, known simply as the Royal Society, is a learned society for science, and is possibly the oldest such society in existence. Founded in November 1660, it was granted a Royal Charter by King Charles II as the "Royal Society of London"...
Research Fellow at the University of Cambridge
University of Cambridge
The University of Cambridge is a public research university located in Cambridge, United Kingdom. It is the second-oldest university in both the United Kingdom and the English-speaking world , and the seventh-oldest globally...
from 1993 to 1996 and has been a Professor at the University of Bath since 1997.
His research interests include evolution, genetics and genomics using computational
Bioinformatics
Bioinformatics is the application of computer science and information technology to the field of biology and medicine. Bioinformatics deals with algorithms, databases and information systems, web technologies, artificial intelligence and soft computing, information and computation theory, software...
and mathematical techniques to understand the way genes and genomes evolve. This has resulted in work on housekeeping gene
Housekeeping gene
A housekeeping gene is typically a constitutive gene that is required for the maintenance of basic cellular function, and are found in all cells of an organism. Although some housekeeping genes are expressed at relatively constant levels , other housekeeping genes may vary depending on...
s, gene orders
Gene orders
Gene orders is the permutation of genome arrangement. So far a fair amount of work trying to describe whether gene orders evolve according to a molecular clock or in jumps ....
and the evolution of drug resistance
Drug resistance
Drug resistance is the reduction in effectiveness of a drug such as an antimicrobial or an antineoplastic in curing a disease or condition. When the drug is not intended to kill or inhibit a pathogen, then the term is equivalent to dosage failure or drug tolerance. More commonly, the term is used...
in Staphylococcus aureus
Staphylococcus aureus
Staphylococcus aureus is a facultative anaerobic Gram-positive coccal bacterium. It is frequently found as part of the normal skin flora on the skin and nasal passages. It is estimated that 20% of the human population are long-term carriers of S. aureus. S. aureus is the most common species of...
, Saccharomyces cerevisiae
Saccharomyces cerevisiae
Saccharomyces cerevisiae is a species of yeast. It is perhaps the most useful yeast, having been instrumental to baking and brewing since ancient times. It is believed that it was originally isolated from the skin of grapes...
and the evolution of sexual reproduction / sexual dimorphism
Sexual dimorphism
Sexual dimorphism is a phenotypic difference between males and females of the same species. Examples of such differences include differences in morphology, ornamentation, and behavior.-Examples:-Ornamentation / coloration:...
.