Lecozotan
Encyclopedia
Lecozotan is an investigational drug by Wyeth
tested for improvement of cognitive functions of Alzheimer's disease
patients.
, the first Phase III clinical trial has been completed.
antagonist
which enhances the potassium-stimulated release of acetylcholine
and glutamate.
Wyeth
Wyeth, formerly one of the companies owned by American Home Products Corporation , was a pharmaceutical company. The company was based in Madison, New Jersey, USA...
tested for improvement of cognitive functions of Alzheimer's disease
Alzheimer's disease
Alzheimer's disease also known in medical literature as Alzheimer disease is the most common form of dementia. There is no cure for the disease, which worsens as it progresses, and eventually leads to death...
patients.
, the first Phase III clinical trial has been completed.
Method of action
Lecozotan is a competitive, selective 5-HT1A receptorReceptor (biochemistry)
In biochemistry, a receptor is a molecule found on the surface of a cell, which receives specific chemical signals from neighbouring cells or the wider environment within an organism...
antagonist
Antagonist
An antagonist is a character, group of characters, or institution, that represents the opposition against which the protagonist must contend...
which enhances the potassium-stimulated release of acetylcholine
Acetylcholine
The chemical compound acetylcholine is a neurotransmitter in both the peripheral nervous system and central nervous system in many organisms including humans...
and glutamate.