Lethal midline granuloma is a condition affecting the nose

Human nose

The visible part of the human nose is the protruding part of the face that bears the nostrils. The shape of the nose is determined by the ethmoid bone and the nasal septum, which consists mostly of cartilage and which separates the nostrils...

 and palate

Palate

The palate is the roof of the mouth in humans and other mammals. It separates the oral cavity from the nasal cavity. A similar structure is found in crocodilians, but, in most other tetrapods, the oral and nasal cavities are not truly separate. The palate is divided into two parts, the anterior...

. The preferred modern term is ulcerating midline lymphoma, as it is by no means always lethal when treated in time.

It has been suggested that the term is confusing and obsolete.

It is sometimes considered to be part of a spectrum with Wegener's granulomatosis

Wegener's granulomatosis

Wegener's granulomatosis , more recently granulomatosis with polyangiitis , is an incurable form of vasculitis that affects the nose, lungs, kidneys and other organs. Due to its end-organ damage, it is life-threatening and requires long-term immunosuppression...

.

It is considered a form of Extranodal NK-T-cell lymphoma.