Lipoprotein lipase deficiency
Encyclopedia
Lipoprotein lipase deficiency (also known as "chylomicronemia,", "chylomicronemia syndrome" and "hyperlipoproteinemia type Ia") is caused by a mutation in the gene which codes lipoprotein lipase
.. As a result, afflicted individuals lack the ability to produce lipoprotein lipase enzymes necessary for effective breakdown of fatty acids.
Lipoprotein lipase
Lipoprotein lipase is a member of the lipase gene family, which includes pancreatic lipase, hepatic lipase, and endothelial lipase. It is a water soluble enzyme that hydrolyzes triglycerides in lipoproteins, such as those found in chylomicrons and very low-density lipoproteins , into two free...
.. As a result, afflicted individuals lack the ability to produce lipoprotein lipase enzymes necessary for effective breakdown of fatty acids.
See also
- Primary hyperlipoproteinemia
- Familial apoprotein CII deficiency
- List of cutaneous conditions