Pittsburgh to Chicago

• Main Line (Pittsburgh to Chicago)
  Fort Wayne Line
  The Fort Wayne Line and Fort Wayne Secondary is a rail line owned and operated by the Norfolk Southern Railway , Chicago, Fort Wayne and Eastern Railroad , and CSX Transportation in the U.S. states of Pennsylvania, Ohio, and Indiana...
  
  
  • Economy Branch (Baden)
  • Block House Run Branch (New Brighton)
  • North Rochester Branch (Rochester)
  • Marginal Branch (Beaver Falls)
  • Oil Street Branch (Beaver Falls)
  • South Canton Branch (Canton)
  • Buck Hill Branch (Canton)
  • South Massillon Branch (Massillon)
  • Massillon and Cleveland Branch (Massillon Junction to Clinton)
  • Walhonding Branch (Loudonville to Coshocton)
  • Rocky Fork Branch (Mansfield)
  • Toledo Branch (Toledo Junction to Detroit)
    • Water Street Branch (Toledo)
    • River Branch (Toledo)
    • Oakman Branch (Dearborn)
    • West Belt Branch (Dearborn to Highland Park)
  • Grand Rapids Branch
    Grand Rapids and Indiana Railroad
    The Grand Rapids and Indiana Railroad at its height provided passenger and freight railroad services between Cincinnati, Ohio and the Straits of Mackinac in Michigan, USA...
    
     (Fort Wayne to Mackinaw City)
    • Muskegon Branch (Grand Rapids to Muskegon)
    • Missaukee Branch (Missakuee Junction to Michelson)
    • Traverse City Branch (Walton Junction to Traverse City)
    • Harbor Springs Branch (Kegomic to Harbor Springs)
  • State Line and Indiana City Railway (Clarke Junction to State Line)
    • Wolf Lake Branch (Hammond)
    • Hammond Branch (Hammond to Hegewisch)
  • South Chicago and Southern Railroad (Colehour to Bernice)
  • Calumet River Line (South Chicago to Hegewisch)
  • Cummings Branch (South Chicago)
  • Calumet Western Railway (South Chicago to Hegewisch)

• Cleveland Line
  Cleveland Line
  Cleveland Line may refer to:*the Cleveland railway line in Brisbane, Australia*the Norfolk Southern Cleveland Line in the United States...
  
   (Rochester to Cleveland)
  • Beaver Valley Railroad Branch (Vanport)
  • River Branch (Yellow Creek to Bellaire)
    • Wheeling Terminal Branch (Martins Ferry to Benwood)
    • POV&C Railroad Branch (Bellaire to Krebs Run)
      • Wegee Branch (Wegee to Webb)
  • Salineville Railroad (Salineville)
  • Canton-Bayard Branch (Bayard to Fairhope)
  • Tuscarawas Branch (Bayard to Goshen)
    • Brush Run Branch (Magnolia)

• • • Marietta Branch (Dover to Marietta)
    • Strasburg Branch (Dover to Parral)
  • Akron Branch (Hudson to Columbus)
    • Dresden Branch (Killbuck to Trinway)
    • Howard Branch (Howard to Millwood)
  • Maple Heights Industrial Branch (Maple Heights to Cleveland)
  • Kingsbury Branch (Cleveland)
  • Silver Plate Branch (Cleveland)

• New Brighton to Ashtabula Harbor
  • Kenwood Branch (New Brighton)
  • Beaver Valley Branch (Homewood Junction to Wampum Junction)
  • Mahoningtown Branch (New Castle Junction to New Castle)
    • Erie and Pittsburgh Branch (New Castle to Erie)
      • Sharpsville Branch (Sharpsville)
    • New Castle Branch
      New Castle Branch (Pennsylvania Railroad)
      The New Castle Branch was a rail line owned and operated by the Pennsylvania Railroad in the U.S. state of Pennsylvania. The line ran from New Castle north to Stoneboro , and is now entirely abandoned. At its south end, the line intersected the Erie and Pittsburgh Branch and Mahoningtown Branch...
      
       (New Castle to Stoneboro)
      • Wilmington Branch
        Wilmington Branch
        Wilmington Branch is a branch library of the Los Angeles Public Library located in the Wilmington section of Los Angeles, California. It was built in 1927 based on a Spanish Colonial Revival design by architect W.E...
        
         (Wilmington Junction to New Wilmington)
      • Wolf Creek Branch (Leesburg to Redmond)
  • Bessemer Branch (Coverts to Walford)
  • Canfield Branch (Haselton)
  • Alliance Branch (Niles to Alliance)

• Sandusky Branch (Sandusky to Columbus)

Pittsburgh to St. Louis

• Main Line (Pittsburgh, PA to St. Louis, MO)
  • Ohio Connecting Railway (Pittsburgh?)

• • • Duffs Branch (Pittsburgh to Carnegie?)
    • Sheridan Branch (Corliss?)
  • Chartiers Branch (Carnegie to Washington)
    • Bridgeville and McDonald Branch (Bridgeville to Cecil)
    • Westland Branch (Houston to Westland)
      • Palanka Branch (Houston to Palanka)
  • Burgetts Branch (Burgettstown to Valear)
    • Hickory Branch (Burgettstown to Cherry Valley)
    • Langeloth Branch (Valear to Studa)
  • New Cumberland Branch (Weirton Junction to Kobuta)
  • Wheeling Branch (Weirton Junction to Benwood)
  • Cadiz Branch (Cadiz Junction to Cadiz)
    • Georgetown Branch (Lando to Georgetown)
  • Zanesville Branch (Trinway to Morrow)
    • Mill Run Branch (Zanesville)

• • Springfield Branch (Xenia to Springfield)
  • C&X Branch (Xenia, OH to Cincinnati, OH)
    • Middletown Branch (Middletown Junction, OH to Middletown, OH)
    • Undercliff Branch (Rendcomb Junction, OH to Cincinnati, OH)

• • • Richmond Branch (Oakley, OH to Anoka, IN)
      • Fort Wayne Branch (Richmond, IN to Adams Township of Allen County, IN
        Allen County, Indiana
        As of the census of 2000, there were 331,849 people, 128,745 households, and 86,259 families residing in the county. The population density was 505 people per square mile . There were 138,905 housing units at an average density of 211 per square mile...
        
        )
  • Lebanon Branch (Cincinnati, OH to Dayton, OH)
    • Montgomery Branch (Blue Ash, OH to Montgomery, OH)
    • Hempstead Branch (Hempstead to Clement)
  • Louisville Branch
    Louisville and Indiana Railroad
    The Louisville and Indiana Railroad is a Class III railroad that operates freight service between Indianapolis, Indiana and Louisville, Kentucky, with a major yard and maintenance shop in Jeffersonville, Indiana....
    
     (Indianapolis, IN to Louisville, KY)
    • Madison Branch (Columbus, IN to Madison, IN)
    • Shelbyville Branch (Columbus, IN to Dublin Junction, IN)
    • New Albany Branch (Jeffersonville, IN to New Albany, IN)

• • • Arbegust Street Branch (Louisville, KY)
  • Vincennes Branch
    Indiana Southern Railroad
    The Indiana Southern Railroad is a short line or Class III railroad operating in the United States state of Indiana. It began operations in 1992, and was acquired by RailAmerica in 2000....
    
     (Indianapolis, IN to Vincennes, IN)

Pittsburgh to Chicago

• Main Line (Pittsburgh to Chicago)
  Fort Wayne Line
  The Fort Wayne Line and Fort Wayne Secondary is a rail line owned and operated by the Norfolk Southern Railway , Chicago, Fort Wayne and Eastern Railroad , and CSX Transportation in the U.S. states of Pennsylvania, Ohio, and Indiana...
  
  
  • Economy Branch (Baden)
  • Block House Run Branch (New Brighton)
  • North Rochester Branch (Rochester)
  • Marginal Branch (Beaver Falls)
  • Oil Street Branch (Beaver Falls)
  • South Canton Branch (Canton)
  • Buck Hill Branch (Canton)
  • South Massillon Branch (Massillon)
  • Massillon and Cleveland Branch (Massillon Junction to Clinton)
  • Walhonding Branch (Loudonville to Coshocton)
  • Rocky Fork Branch (Mansfield)
  • Toledo Branch (Toledo Junction to Detroit)
    • Water Street Branch (Toledo)
    • River Branch (Toledo)
    • Oakman Branch (Dearborn)
    • West Belt Branch (Dearborn to Highland Park)
  • Grand Rapids Branch
    Grand Rapids and Indiana Railroad
    The Grand Rapids and Indiana Railroad at its height provided passenger and freight railroad services between Cincinnati, Ohio and the Straits of Mackinac in Michigan, USA...
    
     (Fort Wayne to Mackinaw City)
    • Muskegon Branch (Grand Rapids to Muskegon)
    • Missaukee Branch (Missakuee Junction to Michelson)
    • Traverse City Branch (Walton Junction to Traverse City)
    • Harbor Springs Branch (Kegomic to Harbor Springs)
  • State Line and Indiana City Railway (Clarke Junction to State Line)
    • Wolf Lake Branch (Hammond)
    • Hammond Branch (Hammond to Hegewisch)
  • South Chicago and Southern Railroad (Colehour to Bernice)
  • Calumet River Line (South Chicago to Hegewisch)
  • Cummings Branch (South Chicago)
  • Calumet Western Railway (South Chicago to Hegewisch)

• Cleveland Line
  Cleveland Line
  Cleveland Line may refer to:*the Cleveland railway line in Brisbane, Australia*the Norfolk Southern Cleveland Line in the United States...
  
   (Rochester to Cleveland)
  • Beaver Valley Railroad Branch (Vanport)
  • River Branch (Yellow Creek to Bellaire)
    • Wheeling Terminal Branch (Martins Ferry to Benwood)
    • POV&C Railroad Branch (Bellaire to Krebs Run)
      • Wegee Branch (Wegee to Webb)
  • Salineville Railroad (Salineville)
  • Canton-Bayard Branch (Bayard to Fairhope)
  • Tuscarawas Branch (Bayard to Goshen)
    • Brush Run Branch (Magnolia)

• • • Marietta Branch (Dover to Marietta)
    • Strasburg Branch (Dover to Parral)
  • Akron Branch (Hudson to Columbus)
    • Dresden Branch (Killbuck to Trinway)
    • Howard Branch (Howard to Millwood)
  • Maple Heights Industrial Branch (Maple Heights to Cleveland)
  • Kingsbury Branch (Cleveland)
  • Silver Plate Branch (Cleveland)

• New Brighton to Ashtabula Harbor
  • Kenwood Branch (New Brighton)
  • Beaver Valley Branch (Homewood Junction to Wampum Junction)
  • Mahoningtown Branch (New Castle Junction to New Castle)
    • Erie and Pittsburgh Branch (New Castle to Erie)
      • Sharpsville Branch (Sharpsville)
    • New Castle Branch
      New Castle Branch (Pennsylvania Railroad)
      The New Castle Branch was a rail line owned and operated by the Pennsylvania Railroad in the U.S. state of Pennsylvania. The line ran from New Castle north to Stoneboro , and is now entirely abandoned. At its south end, the line intersected the Erie and Pittsburgh Branch and Mahoningtown Branch...
      
       (New Castle to Stoneboro)
      • Wilmington Branch
        Wilmington Branch
        Wilmington Branch is a branch library of the Los Angeles Public Library located in the Wilmington section of Los Angeles, California. It was built in 1927 based on a Spanish Colonial Revival design by architect W.E...
        
         (Wilmington Junction to New Wilmington)
      • Wolf Creek Branch (Leesburg to Redmond)
  • Bessemer Branch (Coverts to Walford)
  • Canfield Branch (Haselton)
  • Alliance Branch (Niles to Alliance)

• Sandusky Branch (Sandusky to Columbus)

Pittsburgh to St. Louis

• Main Line (Pittsburgh, PA to St. Louis, MO)
  • Ohio Connecting Railway (Pittsburgh?)

• • • Duffs Branch (Pittsburgh to Carnegie?)
    • Sheridan Branch (Corliss?)
  • Chartiers Branch (Carnegie to Washington)
    • Bridgeville and McDonald Branch (Bridgeville to Cecil)
    • Westland Branch (Houston to Westland)
      • Palanka Branch (Houston to Palanka)
  • Burgetts Branch (Burgettstown to Valear)
    • Hickory Branch (Burgettstown to Cherry Valley)
    • Langeloth Branch (Valear to Studa)
  • New Cumberland Branch (Weirton Junction to Kobuta)
  • Wheeling Branch (Weirton Junction to Benwood)
  • Cadiz Branch (Cadiz Junction to Cadiz)
    • Georgetown Branch (Lando to Georgetown)
  • Zanesville Branch (Trinway to Morrow)
    • Mill Run Branch (Zanesville)

• • Springfield Branch (Xenia to Springfield)
  • C&X Branch (Xenia, OH to Cincinnati, OH)
    • Middletown Branch (Middletown Junction, OH to Middletown, OH)
    • Undercliff Branch (Rendcomb Junction, OH to Cincinnati, OH)

• • • Arbegust Street Branch (Louisville, KY)
  • Vincennes Branch
    Indiana Southern Railroad
    The Indiana Southern Railroad is a short line or Class III railroad operating in the United States state of Indiana. It began operations in 1992, and was acquired by RailAmerica in 2000....
    
     (Indianapolis, IN to Vincennes, IN)

Pittsburgh to Chicago

• Main Line (Pittsburgh to Chicago)
  Fort Wayne Line
  The Fort Wayne Line and Fort Wayne Secondary is a rail line owned and operated by the Norfolk Southern Railway , Chicago, Fort Wayne and Eastern Railroad , and CSX Transportation in the U.S. states of Pennsylvania, Ohio, and Indiana...
  
  
  • Economy Branch (Baden)
  • Block House Run Branch (New Brighton)
  • North Rochester Branch (Rochester)
  • Marginal Branch (Beaver Falls)
  • Oil Street Branch (Beaver Falls)
  • South Canton Branch (Canton)
  • Buck Hill Branch (Canton)
  • South Massillon Branch (Massillon)
  • Massillon and Cleveland Branch (Massillon Junction to Clinton)
  • Walhonding Branch (Loudonville to Coshocton)
  • Rocky Fork Branch (Mansfield)
  • Toledo Branch (Toledo Junction to Detroit)
    • Water Street Branch (Toledo)
    • River Branch (Toledo)
    • Oakman Branch (Dearborn)
    • West Belt Branch (Dearborn to Highland Park)
  • Grand Rapids Branch
    Grand Rapids and Indiana Railroad
    The Grand Rapids and Indiana Railroad at its height provided passenger and freight railroad services between Cincinnati, Ohio and the Straits of Mackinac in Michigan, USA...
    
     (Fort Wayne to Mackinaw City)
    • Muskegon Branch (Grand Rapids to Muskegon)
    • Missaukee Branch (Missakuee Junction to Michelson)
    • Traverse City Branch (Walton Junction to Traverse City)
    • Harbor Springs Branch (Kegomic to Harbor Springs)
  • State Line and Indiana City Railway (Clarke Junction to State Line)
    • Wolf Lake Branch (Hammond)
    • Hammond Branch (Hammond to Hegewisch)
  • South Chicago and Southern Railroad (Colehour to Bernice)
  • Calumet River Line (South Chicago to Hegewisch)
  • Cummings Branch (South Chicago)
  • Calumet Western Railway (South Chicago to Hegewisch)

• Cleveland Line
  Cleveland Line
  Cleveland Line may refer to:*the Cleveland railway line in Brisbane, Australia*the Norfolk Southern Cleveland Line in the United States...
  
   (Rochester to Cleveland)
  • Beaver Valley Railroad Branch (Vanport)
  • River Branch (Yellow Creek to Bellaire)
    • Wheeling Terminal Branch (Martins Ferry to Benwood)
    • POV&C Railroad Branch (Bellaire to Krebs Run)
      • Wegee Branch (Wegee to Webb)
  • Salineville Railroad (Salineville)
  • Canton-Bayard Branch (Bayard to Fairhope)
  • Tuscarawas Branch (Bayard to Goshen)
    • Brush Run Branch (Magnolia)

• • • Marietta Branch (Dover to Marietta)
    • Strasburg Branch (Dover to Parral)
  • Akron Branch (Hudson to Columbus)
    • Dresden Branch (Killbuck to Trinway)
    • Howard Branch (Howard to Millwood)
  • Maple Heights Industrial Branch (Maple Heights to Cleveland)
  • Kingsbury Branch (Cleveland)
  • Silver Plate Branch (Cleveland)

• New Brighton to Ashtabula Harbor
  • Kenwood Branch (New Brighton)
  • Beaver Valley Branch (Homewood Junction to Wampum Junction)
  • Mahoningtown Branch (New Castle Junction to New Castle)
    • Erie and Pittsburgh Branch (New Castle to Erie)
      • Sharpsville Branch (Sharpsville)
    • New Castle Branch
      New Castle Branch (Pennsylvania Railroad)
      The New Castle Branch was a rail line owned and operated by the Pennsylvania Railroad in the U.S. state of Pennsylvania. The line ran from New Castle north to Stoneboro , and is now entirely abandoned. At its south end, the line intersected the Erie and Pittsburgh Branch and Mahoningtown Branch...
      
       (New Castle to Stoneboro)
      • Wilmington Branch
        Wilmington Branch
        Wilmington Branch is a branch library of the Los Angeles Public Library located in the Wilmington section of Los Angeles, California. It was built in 1927 based on a Spanish Colonial Revival design by architect W.E...
        
         (Wilmington Junction to New Wilmington)
      • Wolf Creek Branch (Leesburg to Redmond)
  • Bessemer Branch (Coverts to Walford)
  • Canfield Branch (Haselton)
  • Alliance Branch (Niles to Alliance)

• Sandusky Branch (Sandusky to Columbus)

Pittsburgh to St. Louis

• Main Line (Pittsburgh, PA to St. Louis, MO)
  • Ohio Connecting Railway (Pittsburgh?)

• • • Duffs Branch (Pittsburgh to Carnegie?)
    • Sheridan Branch (Corliss?)
  • Chartiers Branch (Carnegie to Washington)
    • Bridgeville and McDonald Branch (Bridgeville to Cecil)
    • Westland Branch (Houston to Westland)
      • Palanka Branch (Houston to Palanka)
  • Burgetts Branch (Burgettstown to Valear)
    • Hickory Branch (Burgettstown to Cherry Valley)
    • Langeloth Branch (Valear to Studa)
  • New Cumberland Branch (Weirton Junction to Kobuta)
  • Wheeling Branch (Weirton Junction to Benwood)
  • Cadiz Branch (Cadiz Junction to Cadiz)
    • Georgetown Branch (Lando to Georgetown)
  • Zanesville Branch (Trinway to Morrow)
    • Mill Run Branch (Zanesville)

• • Springfield Branch (Xenia to Springfield)
  • C&X Branch (Xenia, OH to Cincinnati, OH)
    • Middletown Branch (Middletown Junction, OH to Middletown, OH)
    • Undercliff Branch (Rendcomb Junction, OH to Cincinnati, OH)

• • • Arbegust Street Branch (Louisville, KY)
  • Vincennes Branch
    Indiana Southern Railroad
    The Indiana Southern Railroad is a short line or Class III railroad operating in the United States state of Indiana. It began operations in 1992, and was acquired by RailAmerica in 2000....
    
     (Indianapolis, IN to Vincennes, IN)

• • • Greene County Coal Branch (Bushrod, IN to Linton, IN)
    • Columbia Branch (Bicknell, IN)
    • Knox County Coal Branch (Bicknell, IN)
  • I&F Branch
  • Centerpoint Branch (Stearleys to Centerpoint)
  • Hadleytown Branch (Brazil to Hadleytown)
  • Saline City Branch (Brazil)
  • Willow Creek Branch (Staunton to Seelyville)
  • Furnace Branch (Brazil)
  • Glen Ayr Branch (Seelyville)
  • Crawfordsville Branch (Terre Haute to Frankfort)
  • Macksville North Branch (West Terre Haute)
  • Macksville South Branch (West Terre Haute)
  • Peoria Branch (Farrington to Peoria)
  • Highland Mill Branch (Highland)
  • Troy Branch (Collinsville to Troy)
  • Stock Yards Branch (East St. Louis, IL)

Columbus to Chicago

• Main Line (Columbus, OH to Chicago, IL)
  • Main Line (Columbus to Indianapolis via Bradford)
    Main Line (Columbus to Indianapolis via Bradford)
    The Columbus to Indianapolis via Bradford Main Line was a rail line owned and operated by the Pennsylvania Railroad in the U.S. state of Ohio.The line ran from Bradford on the Columbus to Chicago Main Line southwest to New Paris on the Pittsburgh to St. Louis Main Line, forming part of a route...
    
     (Bradford, OH to New Paris, OH)
  • Muncie Branch (Converse, IN to Muncie, IN)
  • South Bend Branch
    South Bend Branch
    The South Bend Branch was a Pennsylvania Railroad line that ran from South Bend, Indiana to Logansport, Indiana. The line was built in 1883 and was then a part of the Vandalia Railroad...
    
     (Logansport, IN to South Bend, IN)
    • Butler Branch
      Butler Branch (Indiana)
      The Butler Branch is a historic railroad line that operated in Indiana, USA. It ran between the city of Logansport on the Wabash River in north central Indiana and the namesake town of Butler near the Ohio border in northeastern Indiana....
      
       (Logansport, IN to Butler, IN)

• • Effner Branch (Kenneth, IN to Effner, IL)
  • Englewood Connecting Railway Branch (Chicago, IL)