Loteprednol is a corticosteroid

Corticosteroid

Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte...

 used in ophthalmology

Ophthalmology

Ophthalmology is the branch of medicine that deals with the anatomy, physiology and diseases of the eye. An ophthalmologist is a specialist in medical and surgical eye problems...

. Marketed by Bausch and Lomb as Lotemax in the U.S., ocular applications for this drug include the treatment of inflammation of the eye due to allergies (according to the prescription information sheet), as well as chronic forms of keratitis

Keratitis

Keratitis is a condition in which the eye's cornea, the front part of the eye, becomes inflamed. The condition is often marked by moderate to intense pain and usually involves impaired eyesight.-Types:...

 (e.g.: adenoviral and Thygeson’s keratitis

Thygeson's superficial punctate keratopathy

Thygeson's superficial punctate keratopathy is a disease of the eyes. The causes of TSPK are not currently known, but details of the disease were first published in the Journal of the American Medical Association in 1950 by Phillips Thygeson - after whom it is named.- Symptoms :A patient with TSPK...

), vernal keratoconjunctivitis

Vernal keratoconjunctivitis

Vernal keratoconjunctivitis or Spring catarrh is a recurrent, bilateral, and self limiting inflammation of conjunctiva, having a periodic seasonal incidence.-Etiology:...

, pingueculitis

Pinguecula

A pinguecula is a common type of conjunctival degeneration in the eye.-Presentation:It is seen as a yellow- white deposit on the conjunctiva adjacent to the limbus . It is to be distinguished clinically from pterygium, which is a wedge shaped area of fibrosis that appears to grow into the cornea....

, and episcleritis. The drug has little or no effect on intraocular pressure

Intraocular pressure

Intraocular pressure is the fluid pressure inside the eye. Tonometry is the method eye care professionals use to determine this. IOP is an important aspect in the evaluation of patients at risk from glaucoma...

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Druzgala, P.; Hochhaus, G.; Bodor, N.; J. Steroid Biochem. Mol. Biol. 1991, 38, 149.

http://dx.doi.org/10.1016/0960-0760(91)90120-T