Ludolf von Krehl
Encyclopedia
Albrecht Ludolf von Krehl (December 26, 1861 - May 26, 1937) was a German internist and physiologist who was a native of Leipzig
. He was the son of Orientalist
Christoph Krehl
(1825-1901)
He studied at the Universities of Heidelberg and Leipzig
, and later was an assistant to Ernst Leberecht Wagner
(1829-1888) and Heinrich Curschmann
(1846-1910) at the medical clinic in Leipzig. Afterwards he worked at several university medical clinics, including the University of Strasbourg
and the University of Heidelberg
(1907-1932). One of his better known assistants at Heidelberg
was Viktor von Weizsäcker
(1886-1957).
Krehl is remembered for his work involving heart disorders and his research concerning the physiological and pathological aspects of thermoregulation
, the circulatory system
, et al. Krehl admired the psychoanalytic work of Sigmund Freud
and Josef Breuer
, and had a keen interest in psychopathological
aspects of disease from an individualized, psychosomatic standpoint. While at Strasbourg
, he provided the necessary facilities to Albert Fraenkel
(1864-1938) for the latter's testing of intravenous strophanthin.
Among his written works was a landmark textbook on pathological
physiology that laid a scientific basis for clinical medicine
. This textbook was first published in 1893 as Grundriß der allgemeinen klinischen Pathologie (Later known as Pathologische Physiologie), and eventually ran to fourteen editions. Krehl was a catalyst behind the founding of the "Kaiser Wilhelm Institute for Medical Research", which today is known as the Max Planck Institute for Medical Research
in Heidelberg.
Leipzig
Leipzig Leipzig has always been a trade city, situated during the time of the Holy Roman Empire at the intersection of the Via Regia and Via Imperii, two important trade routes. At one time, Leipzig was one of the major European centres of learning and culture in fields such as music and publishing...
. He was the son of Orientalist
Oriental studies
Oriental studies is the academic field of study that embraces Near Eastern and Far Eastern societies and cultures, languages, peoples, history and archaeology; in recent years the subject has often been turned into the newer terms of Asian studies and Middle Eastern studies...
Christoph Krehl
Christoph Krehl
Christoph Ludolf Ehrenfried Krehl was a German Orientalist, born at Meissen, and educated at Leipzig, Tübingen, Paris, and Saint Petersburg...
(1825-1901)
He studied at the Universities of Heidelberg and Leipzig
University of Leipzig
The University of Leipzig , located in Leipzig in the Free State of Saxony, Germany, is one of the oldest universities in the world and the second-oldest university in Germany...
, and later was an assistant to Ernst Leberecht Wagner
Ernst Leberecht Wagner
Ernst Leberecht Wagner was a German pathologist who was a native of Dehlitz, a town in the Burgenlandkreis district of Saxony-Anhalt. He studied medicine in Leipzig under Karl August Wunderlich , in Prague under Josef Skoda and in Vienna under Karl von Rokitansky...
(1829-1888) and Heinrich Curschmann
Heinrich Curschmann
Heinrich Curschmann was a German internist who was a native of Giessen. Prior to 1888 he worked in hospitals in Berlin and Hamburg...
(1846-1910) at the medical clinic in Leipzig. Afterwards he worked at several university medical clinics, including the University of Strasbourg
University of Strasbourg
The University of Strasbourg in Strasbourg, Alsace, France, is the largest university in France, with about 43,000 students and over 4,000 researchers....
and the University of Heidelberg
Heidelberg
-Early history:Between 600,000 and 200,000 years ago, "Heidelberg Man" died at nearby Mauer. His jaw bone was discovered in 1907; with scientific dating, his remains were determined to be the earliest evidence of human life in Europe. In the 5th century BC, a Celtic fortress of refuge and place of...
(1907-1932). One of his better known assistants at Heidelberg
Heidelberg
-Early history:Between 600,000 and 200,000 years ago, "Heidelberg Man" died at nearby Mauer. His jaw bone was discovered in 1907; with scientific dating, his remains were determined to be the earliest evidence of human life in Europe. In the 5th century BC, a Celtic fortress of refuge and place of...
was Viktor von Weizsäcker
Viktor von Weizsäcker
Viktor Freiherr von Weizsäcker was a German physician and physiologist. He was the brother of Ernst von Weizsäcker, and uncle to Richard von Weizsäcker and Carl Friedrich von Weizsäcker. .He studied at Tübingen, Freiburg, Berlin, and Heidelberg, where he earned his medical degree in 1910...
(1886-1957).
Krehl is remembered for his work involving heart disorders and his research concerning the physiological and pathological aspects of thermoregulation
Thermoregulation
Thermoregulation is the ability of an organism to keep its body temperature within certain boundaries, even when the surrounding temperature is very different...
, the circulatory system
Circulatory system
The circulatory system is an organ system that passes nutrients , gases, hormones, blood cells, etc...
, et al. Krehl admired the psychoanalytic work of Sigmund Freud
Sigmund Freud
Sigmund Freud , born Sigismund Schlomo Freud , was an Austrian neurologist who founded the discipline of psychoanalysis...
and Josef Breuer
Josef Breuer
Josef Breuer was an Austrian physician whose works laid the foundation of psychoanalysis.Born in Vienna, his father, Leopold Breuer, taught religion in Vienna's Jewish community. Breuer's mother died when he was quite young, and he was raised by his maternal grandmother and educated by his father...
, and had a keen interest in psychopathological
Psychopathology
Psychopathology is the study of mental illness, mental distress, and abnormal/maladaptive behavior. The term is most commonly used within psychiatry where pathology refers to disease processes...
aspects of disease from an individualized, psychosomatic standpoint. While at Strasbourg
Strasbourg
Strasbourg is the capital and principal city of the Alsace region in eastern France and is the official seat of the European Parliament. Located close to the border with Germany, it is the capital of the Bas-Rhin département. The city and the region of Alsace are historically German-speaking,...
, he provided the necessary facilities to Albert Fraenkel
Albert Fraenkel
Albert Fraenkel was a German physician who helped establish Streptococcus pneumoniae as a cause of bacterial pneumonia and championed intravenous ouabain for use in heart failure...
(1864-1938) for the latter's testing of intravenous strophanthin.
Among his written works was a landmark textbook on pathological
Pathology
Pathology is the precise study and diagnosis of disease. The word pathology is from Ancient Greek , pathos, "feeling, suffering"; and , -logia, "the study of". Pathologization, to pathologize, refers to the process of defining a condition or behavior as pathological, e.g. pathological gambling....
physiology that laid a scientific basis for clinical medicine
Clinical Medicine
Clinical Medicine is a peer-reviewed medical journal published bimonthly by the Royal College of Physicians. It was established in 1966 as the Journal of the Royal College of Physicians of London. It was doubly named between 1998 and 2000, and since 2001 it has appeared as Clinical Medicine. Its...
. This textbook was first published in 1893 as Grundriß der allgemeinen klinischen Pathologie (Later known as Pathologische Physiologie), and eventually ran to fourteen editions. Krehl was a catalyst behind the founding of the "Kaiser Wilhelm Institute for Medical Research", which today is known as the Max Planck Institute for Medical Research
Max Planck Institute for Medical Research
The Max Planck Institute for Medical Research in Heidelberg, Germany, is a facility of the Max Planck Society for basic medical research. Since its foundation, six Nobel Prize laureates worked at the Institute: Otto Fritz Meyerhof , Richard Kuhn , Walther Bothe , André Michel Lwoff , Rudolf...
in Heidelberg.
Selected writings
- Grundriß der allgemeinen klinischen Pathologie, (Fundamentals of General Clinical Pathology), later known as Pathologische Physiologie (Pathological Physiology); Leipzig (1893)
- Die Erkrankungen des Herzmuskels, In: Carl NothnagelCarl NothnagelCarl Wilhelm Hermann Nothnagel was a German internist born in Alt-Lietzegöricke , nearby Bärwalde in der Neumark , Neumark, Brandenburg....
's: Experimentelle Pathologie und Therapie, Bd. 15/1, Holder, Wien (1901) - Krankheitsform und Persönlichkeit, Thieme, Leipzig (1929)
- Über die Naturheilkunde, (1935)