Lutheran antigen system
Encyclopedia
Lutheran antigen system is a human blood group system
based upon genes on chromosome 19.
This system is a single locus system, with antigens Lua and Lub. The Lu(b) negative phenotype is very rare. Antibodies to Lutheran antigens are IgG. The genes of the Lutheran group are linked to the genes responsible for the secretion of ABH substances.
A complex blood group system having pairs of alternate antigens and amorphic genes, but also subject to a dominant independently segregating repressor.
Human blood group systems
The International Society of Blood Transfusion currently recognises 30 major blood group systems . Thus, in addition to the ABO antigens and Rhesus antigens, many other antigens are expressed on the red blood cell surface membrane...
based upon genes on chromosome 19.
This system is a single locus system, with antigens Lua and Lub. The Lu(b) negative phenotype is very rare. Antibodies to Lutheran antigens are IgG. The genes of the Lutheran group are linked to the genes responsible for the secretion of ABH substances.
A complex blood group system having pairs of alternate antigens and amorphic genes, but also subject to a dominant independently segregating repressor.
External links
- Lutheran at BGMUTBGMUTThe BGMUT Database documents allelic variations in the genes encoding for human blood group systems. It was set up in 1999 through an initiative of the Human Genome Variation Society . Since 2006, it has been a part of the dbRBC resource of NCBI at the NIH...
Blood Group Antigen Gene Mutation Database at NCBINational Center for Biotechnology InformationThe National Center for Biotechnology Information is part of the United States National Library of Medicine , a branch of the National Institutes of Health. The NCBI is located in Bethesda, Maryland and was founded in 1988 through legislation sponsored by Senator Claude Pepper...
, NIH