Lymphomatoid papulosis (LyP) is a rare skin disorder. The overall prevalence rate of lymphomatoid papulosis is estimated at 1.2 to 1.9 cases per 1,000,000 population.

This rare condition has only been studied in depth since 1968.

Presentation

It can appear very similar to anaplastic large cell lymphoma

Anaplastic large cell lymphoma

Anaplastic large-cell lymphoma is a type of non-Hodgkin lymphoma that features in the World Health Organisation classification of lymphomas.Its name derives from anaplasia and large-cell lymphoma.-Signs and symptoms:...

.

Type "A" is CD30

CD30

CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker.This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the...

 positive, while type "B" is CD30 negative.

It has been described as "clinically benign but histologically malignant."

See also

• Cutaneous T-cell lymphoma
• Parapsoriasis
  Parapsoriasis
  Parapsoriasis refers to one of a group of skin disorders that are characterized primarily by their resemblance to psoriasis , rather than by their underlying etiology.Neoplasms can develop from parapsoriasis...
  
  
• Secondary cutaneous CD30+ large cell lymphoma
  Secondary cutaneous CD30+ large cell lymphoma
  Secondary cutaneous CD30+ large-cell lymphoma is a cutaneous condition that may arise in cases of mycosis fungoides, and in patients with lymphomatoid papulosis.- See also :* Cutaneous T-cell lymphoma* CD30+ cutaneous T-cell lymphoma* Skin lesion...
  
  
• List of cutaneous conditions