MYLK4
Encyclopedia
Myosin light chain kinase 4 also known as MYLK4 is an enzyme
which in humans is encoded by the MYLK2 gene
. MYLK4 is a member of the myosin light-chain kinase
family of serine/threonine-specific protein kinase
s that phosphorylate the regulatory light chain of myosin II.
This protein acts as an enzyme that catalyzes the following reaction: ATP + a protein -> ADP + a phosphoprotein.
MYLK4 is also involved in protein amino acid phosphorylation meaning that it adds a phosphate group onto the molecule.
Not very much is known about the specific functional characteristics of MLYK4, but it has recently been found that the gene may possibly have a role in having at least one driver mutation for cancer.
MYLK4 may also be involved in transferase activity, ATP binding, protein serine/threonine kinase activity, and also nucleotide binding.
Other names for MYLK4 are CaMLCK like; EG238564; MYLK4; Mylk4; Myosin light chain kinase family, member 4; SgK085; SGK085; Sgk085; Sugen kinase 85; Uncharacterized serine/threonine-protein kinase SgK085.
The “Sgk” in the Sgk085 name for MYLK4 stands for to serum- and glucocorticoid-inducible kinases. These are serine/threonine protein kinases (SGKs) whose transcripition is kept in check by cell volume, corticoids, and serum.
There are other known myosin light-chain kinase
enzymes.
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
which in humans is encoded by the MYLK2 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
. MYLK4 is a member of the myosin light-chain kinase
Myosin light-chain kinase
Myosin light-chain kinase also known as MYLK or MLCK is a serine/threonine-specific protein kinase that phosphorylates the regulatory light chain of myosin II.- Isoforms :Four different MLCK isoforms exist:* MYLK – smooth muscle...
family of serine/threonine-specific protein kinase
Serine/threonine-specific protein kinase
Serine/threonine protein kinases phosphorylate the OH group of serine or threonine .At least 125 of the 500+ human protein kinases are serine/threonine kinases .-Regulation:...
s that phosphorylate the regulatory light chain of myosin II.
This protein acts as an enzyme that catalyzes the following reaction: ATP + a protein -> ADP + a phosphoprotein.
MYLK4 is also involved in protein amino acid phosphorylation meaning that it adds a phosphate group onto the molecule.
Not very much is known about the specific functional characteristics of MLYK4, but it has recently been found that the gene may possibly have a role in having at least one driver mutation for cancer.
MYLK4 may also be involved in transferase activity, ATP binding, protein serine/threonine kinase activity, and also nucleotide binding.
Other names for MYLK4 are CaMLCK like; EG238564; MYLK4; Mylk4; Myosin light chain kinase family, member 4; SgK085; SGK085; Sgk085; Sugen kinase 85; Uncharacterized serine/threonine-protein kinase SgK085.
The “Sgk” in the Sgk085 name for MYLK4 stands for to serum- and glucocorticoid-inducible kinases. These are serine/threonine protein kinases (SGKs) whose transcripition is kept in check by cell volume, corticoids, and serum.
There are other known myosin light-chain kinase
Myosin light-chain kinase
Myosin light-chain kinase also known as MYLK or MLCK is a serine/threonine-specific protein kinase that phosphorylates the regulatory light chain of myosin II.- Isoforms :Four different MLCK isoforms exist:* MYLK – smooth muscle...
enzymes.