Marcus Raichle
Encyclopedia
Marcus Raichle is a neurologist at the Washington University School of Medicine
in Saint Louis. He is a professor in the Department of Radiology with joint appointments in Neurology, Neurobiology and Biomedical Engineering. His research over the past 40 years has focused on the nature of functional brain imaging signals
arising from PET
and fMRI
and the application of these techniques to the study of the human brain
in health and disease.
of brain function (i.e., organized intrinsic activity) and its signature system, the brain’s default mode network
; and, the discovery that aerobic glycolysis contributes to brain function independent of oxidative phosphorylation
.
Washington University School of Medicine
Washington University School of Medicine , located in St. Louis, Missouri, is one of the graduate schools of Washington University in St. Louis. One of the top medical schools in the United States, it is currently ranked 4th for research according to U.S. News and World Report and has been listed...
in Saint Louis. He is a professor in the Department of Radiology with joint appointments in Neurology, Neurobiology and Biomedical Engineering. His research over the past 40 years has focused on the nature of functional brain imaging signals
Neuroimaging
Neuroimaging includes the use of various techniques to either directly or indirectly image the structure, function/pharmacology of the brain...
arising from PET
Positron emission tomography
Positron emission tomography is nuclear medicine imaging technique that produces a three-dimensional image or picture of functional processes in the body. The system detects pairs of gamma rays emitted indirectly by a positron-emitting radionuclide , which is introduced into the body on a...
and fMRI
Functional magnetic resonance imaging
Functional magnetic resonance imaging or functional MRI is a type of specialized MRI scan used to measure the hemodynamic response related to neural activity in the brain or spinal cord of humans or other animals. It is one of the most recently developed forms of neuroimaging...
and the application of these techniques to the study of the human brain
Brain
The brain is the center of the nervous system in all vertebrate and most invertebrate animals—only a few primitive invertebrates such as sponges, jellyfish, sea squirts and starfishes do not have one. It is located in the head, usually close to primary sensory apparatus such as vision, hearing,...
in health and disease.
Career
Noteworthy accomplishments during this time have been the discovery of the relative independence of blood flow and oxygen consumption during changes in brain activity which provided the physiological basis of fMRI ; the discovery of a default modeDefault network
The default network is a network of brain regions that are active when the individual is not focused on the outside world and the brain is at wakeful rest. Also called the default mode network , default state network, or task-negative network , it is characterized by coherent neuronal oscillations...
of brain function (i.e., organized intrinsic activity) and its signature system, the brain’s default mode network
Default network
The default network is a network of brain regions that are active when the individual is not focused on the outside world and the brain is at wakeful rest. Also called the default mode network , default state network, or task-negative network , it is characterized by coherent neuronal oscillations...
; and, the discovery that aerobic glycolysis contributes to brain function independent of oxidative phosphorylation
Oxidative phosphorylation
Oxidative phosphorylation is a metabolic pathway that uses energy released by the oxidation of nutrients to produce adenosine triphosphate . Although the many forms of life on earth use a range of different nutrients, almost all aerobic organisms carry out oxidative phosphorylation to produce ATP,...
.
Works
Professional memberships
- Member: National Academy of Sciences, Institute of Medicine, American Academy of Arts and Sciences.
- Fellow: American Association Advancement of Science.
Professional societies
- Society for Neuroscience
- American Neurological Association
- American Academy Neurology
- International Society Cerebral Blood Flow & Metabolism.