Margherita Gonzaga was the eldest daughter of Vincenzo I Gonzaga and Eleonora de' Medici

Eleonora de' Medici

Eleonora de' Medici was the eldest child of Francesco I de' Medici and Johanna of Austria. She was a family member of the famous House of Medici.-Family:...

; she was also a sister of Francesco IV Gonzaga

Francesco IV Gonzaga

Francesco IV Gonzaga , was Duke of Mantua and Duke of Montferrat between 9 February and 22 December 1612.-Biography:Born in Mantua, he was the eldest son of Duke Vincenzo I and Eleonora de' Medici....

, Ferdinando I Gonzaga

Ferdinando I Gonzaga

Ferdinand I Gonzaga was Duke of Mantua and Duke of Montferrat from 1612 until his death.-Biography:Born in Mantua, he was the son of Vincent I Gonzaga and Eleonora de' Medici....

, Vincenzo II Gonzaga

Vincenzo II Gonzaga, Duke of Mantua

Vincent II Gonzaga was Duke of Mantua and Duke of Montferrat from 1626 until his death.He was the son of Duke Vincent I and Eleonora de' Medici and inherited the duchy at the death of his elder brother Ferdinand, receiving the imperial investiture on February 8, 1627...

 and Eleonora Gonzaga. Her brothers all succeeded their father as Duke of Mantua and Eleonora became Holy Roman Empress by her marriage to Ferdinand II, Holy Roman Emperor

Ferdinand II, Holy Roman Emperor

Ferdinand II , a member of the House of Habsburg, was Holy Roman Emperor , King of Bohemia , and King of Hungary . His rule coincided with the Thirty Years' War.- Life :...

.

Marriage

She married Henry II, Duke of Lorraine

Henry II, Duke of Lorraine

Henry II was Duke of Lorraine from 1608 until his death. His two daughters were Duchesses of Lorraine by marriage. He was also the brother-in-law of King Henry IV of France.-History and Family:...

 on 24 April 1606. He had previously been married to Catherine of Navarre, sister of King Henry IV of France, but the marriage was childless due to the bride's age (Catherine was forty years old at the time of her marriage).

Henry and Margherita had four children; two of whom survived infancy, they were:

• Nicolette
  Nicolette of Lorraine
  Nicole de Lorraine was Duchess of Lorraine and Bar from 1 August 1624 to 21 November 1625, and Duchess consort in 1625–1634. She was born in Nancy, the daughter of Henry II, Duke of Lorraine and Bar, and Margerita Gonzaga...
  
   (1608–1657), married Charles IV, Duke of Lorraine
  Charles IV, Duke of Lorraine
  Charles IV was Duke of Lorraine from 1624 to 1634, when he abdicated under French pressure in favor of his younger brother, and again from 1661 until 1675.- Biography :...
  
  
• Claude
  Claude of Lorraine (1612-1648)
  Claude de Lorraine was a daughter of Henry II, Duke of Lorraine and Margerita Gonzaga, her sister was Nicole, Duchess of Lorraine. She is also known as Claude Françoise de Lorraine, she married her first cousin and was the Duchess of Lorraine by marriage. Her maternal grandparents were, Vincenzo I...
  
   (1612–1648), married Nicholas II, Duke of Lorraine
  Nicholas II, Duke of Lorraine
  Nicholas Francis , also known as Nicholas II, was briefly Duke of Lorraine and Duke of Bar for a few months in 1634, spanning the time between the abdication of his older brother and his own resignation...
  
  

Both of Margherita's two daughters married their cousins, who were Henry's successors due to the fact that Margherita had not given him a son to inherit his estates.

Death

Margherita died in Nancy in 1632 at the age of forty. She had been a widow since 1624.

Ancestry