"Medicine" is the first promo single of American hip hop rapper Plies

Plies (rapper)

Algernod Lanier Washington , better known by his stage name Plies, is an American rapper and founder of Big Gates Records. Born in Fort Myers, Florida, Washington was a wide receiver on the football team of Miami University in Ohio in 1996 and 1997 before he became a rapper. After dropping out of...

' fourth studio album, Goon Affiliated

Goon Affiliated

Goon Affiliated is the fourth studio album by American rapper Plies. The album was released by Atlantic Records on June 8, 2010.- Background :...

. The track is absent from the retail versions for unknown reasons, but is on the Amazon deluxe version. The track features American singer-songwriter Keri Hilson

Keri Hilson

Keri Lynn Hilson is an American R&B singer-songwriter. Born and raised in Decatur, Georgia, Hilson began her music career as a songwriter, penning tracks for several artists in the mid-2000s as part of the five-person production and songwriting team, The Clutch...

. There are two versions, one with a more radio friendly, slow beat and one with a more club beat.

The original version of the song was by Three 6 Mafia

Three 6 Mafia

Three 6 Mafia are an Academy Award-winning, American rap group originating from Memphis, Tennessee. Formed in 1991 as Triple 6 Mafia, by DJ Paul, Juicy J, & Lord Infamous, the group at its most featured six members including; Crunchy Black, Gangsta Boo and Koopsta Knicca...

 ft. Gucci Mane

Gucci Mane

Radric Davis , better known by his stage name Gucci Mane, is an American rapper. He debuted in 2005 with Trap House and followed with albums such as Hard to Kill in 2006, Trap-A-Thon and Back to the Trap House in 2007. In 2009, his second studio album The State vs. Radric Davis was released...

 & Keri Hilson

Keri Hilson

Keri Lynn Hilson is an American R&B singer-songwriter. Born and raised in Decatur, Georgia, Hilson began her music career as a songwriter, penning tracks for several artists in the mid-2000s as part of the five-person production and songwriting team, The Clutch...

 under the same title. The tempo is somewhat slower in that version.

The song contains a sample of "Ex fan des sixties

Ex fan des sixties

Ex-fan des sixties is the name of an album by Jane Birkin. The album was released in 1978. All songs on the album are by Serge Gainsbourg.-Track listing:#Ex-fan des sixties #Apocalypstick #Exercice en forme de Z...

" by Jane Birkin

Jane Birkin

Jane Mallory Birkin, OBE is an English-born actress and singer who lives in France. In recent years she has written her own album, directed a film and become an outspoken proponent of democracy in Burma.- Early life :...

 and composed by French singer and songwriter Serge Gainsbourg

Serge Gainsbourg

Serge Gainsbourg, born Lucien Ginsburg was a French singer-songwriter, actor and director. Gainsbourg's extremely varied musical style and individuality make him difficult to categorize...

.

Music video

A music video was shot for the song and premiered on January 14, 2010. It takes place in a hospital where Keri Hilson

Keri Hilson

Keri Lynn Hilson is an American R&B singer-songwriter. Born and raised in Decatur, Georgia, Hilson began her music career as a songwriter, penning tracks for several artists in the mid-2000s as part of the five-person production and songwriting team, The Clutch...

 plays a nurse and Plies

Plies (rapper)

Algernod Lanier Washington , better known by his stage name Plies, is an American rapper and founder of Big Gates Records. Born in Fort Myers, Florida, Washington was a wide receiver on the football team of Miami University in Ohio in 1996 and 1997 before he became a rapper. After dropping out of...

 is the doctor which makes reference to the song. Myammee from VH1

VH1

VH1 or Vh1 is an American cable television network based in New York City. Launched on January 1, 1985 in the old space of Turner Broadcasting's short-lived Cable Music Channel, the original purpose of the channel was to build on the success of MTV by playing music videos, but targeting a slightly...

 also makes a cameo in the beginning of the video.

Chart performance

Chart (2009–2010)	Peak position
US Bubbling Under Hot 100 Singles Bubbling Under Hot 100 Singles The Bubbling Under Hot 100 Singles is a chart published weekly by Billboard magazine in the United States. It lists the top 25 singles below number 100 that have not yet charted on the Billboard Hot 100. Sometimes, however, singles halt their progress on this chart, and never appear on the Hot 100...  (Billboard Billboard (magazine) Billboard is a weekly American magazine devoted to the music industry, and is one of the oldest trade magazines in the world. It maintains several internationally recognized music charts that track the most popular songs and albums in various categories on a weekly basis... )	8
US Hot R&B/Hip-Hop Songs Hot R&B/Hip-Hop Songs Hot R&B/Hip-Hop Songs, is a chart released weekly by Billboard in the United States.The chart, initiated in 1942, is used to track the success of popular music songs in urban, or primarily African American, venues. Dominated over the years at various times by jazz, rhythm and blues, doo-wop, soul,...  (Billboard Billboard (magazine) Billboard is a weekly American magazine devoted to the music industry, and is one of the oldest trade magazines in the world. It maintains several internationally recognized music charts that track the most popular songs and albums in various categories on a weekly basis... )	47
US Rap Songs (Billboard Billboard (magazine) Billboard is a weekly American magazine devoted to the music industry, and is one of the oldest trade magazines in the world. It maintains several internationally recognized music charts that track the most popular songs and albums in various categories on a weekly basis... )	21