Meningohydroencephalocoele (AmE

AME

Ame, AME, or AmE may refer to* Anomalous Microwave Emission* Amé, a soft drink* Adaptive multithreaded encryption* African Methodist Episcopal Church* African Methodist Episcopal Zion Church* AME Accounting Software...

: meningohydroencephalocele) is a form of meningocele (AmE

AME

Ame, AME, or AmE may refer to* Anomalous Microwave Emission* Amé, a soft drink* Adaptive multithreaded encryption* African Methodist Episcopal Church* African Methodist Episcopal Zion Church* AME Accounting Software...

) - a developmental abnormality of the central nervous system.

Like meningocoele, meningohydroencephalocoele is caused by defects in bone ossification; in particular, the intramembranous ossification

Ossification

Ossification is the process of laying down new bone material by cells called osteoblasts. It is synonymous with bone tissue formation...

 related to the closure of infantile fontanelles. It refers to the protrusion of the meninges

Meninges

The meninges is the system of membranes which envelopes the central nervous system. The meninges consist of three layers: the dura mater, the arachnoid mater, and the pia mater. The primary function of the meninges and of the cerebrospinal fluid is to protect the central nervous system.-Dura...

 between the un-fused bones, to lie subcutaneously.

• Meningocoele - refers to herniation of meninges.

• Meningoencephalocoele refers to the condition if brain tissue is included with the meninges in the herniation.

• Meningohydroencephalocoele refers to the condition including meninges, brain tissue and part of the ventricular system in the herniation.

These defects occur in approximately 1 in 2000 live births

External links

• Transphenoidal meningohydroencephalocoele, Durham et al. - PubMed