Mesial temporal sclerosis is a specific pattern of hippocampal neuron

Neuron

A neuron is an electrically excitable cell that processes and transmits information by electrical and chemical signaling. Chemical signaling occurs via synapses, specialized connections with other cells. Neurons connect to each other to form networks. Neurons are the core components of the nervous...

 cell loss . There are 3 specific patterns of cell loss; Cell loss might involve sectors CA1 and CA4, CA4 alone, or CA1 to CA4 . Associated hippocampal atrophy

Atrophy

Atrophy is the partial or complete wasting away of a part of the body. Causes of atrophy include mutations , poor nourishment, poor circulation, loss of hormonal support, loss of nerve supply to the target organ, disuse or lack of exercise or disease intrinsic to the tissue itself...

 and gliosis

Gliosis

Gliosis is a proliferation of astrocytes in damaged areas of the central nervous system . This proliferation usually leads to the formation of a glial scar....

 is common. MRI scan commonly displays increased T2 signal and hippocampal atrophy Mesial temporal sclerosis might occur with other temporal lobe abnormalities (dual pathology) . Mesial temporal sclerosis is the most common pathological abnormality in temporal lobe epilepsy

Temporal lobe epilepsy

Temporal lobe epilepsy a.k.a. Psychomotor epilepsy, is a form of focal epilepsy, a chronic neurological condition characterized by recurrent seizures. Over 40 types of epilepsies are known. They fall into two main categories: partial-onset epilepsies and generalized-onset epilepsies...

.

External links

• Mesial Temporal Sclerosis MedPix(r) Images